Ankyrin Repeat Domain

Ankyrin repeat domains (ARDs) are protein regions found within a wide range of proteins. They consist of several repeating sequences of amino acids, usually between 20 and 30 amino acids, folded within a loop-like structure. ARDs are involved in important cellular functions, such as cytoskeletal organization, signal transduction and gene regulation. Due to their diverse roles, ARDs are crucial for the development, survival and function of many organisms. Furthermore, a growing number of studies suggest that ARDs are associated with various diseases, making them a promising target for drug development. ARDs can be found in both prokaryotic and eukaryotic organisms, including humans.


From: International Journal of Amino Acids

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