Overview
Broth microdilution is a standardized laboratory method for determining the susceptibility of microorganisms to antimicrobial agents. In this technique, a series of two-fold dilutions of an antibiotic or antifungal drug is prepared in liquid growth medium, usually in the wells of a microtiter plate, and each is inoculated with a standardized quantity of the test organism. After incubation, the wells are examined for visible growth, and the lowest concentration that prevents growth is recorded as the minimum inhibitory concentration (MIC). The MIC provides a quantitative measure of how much drug is needed to inhibit a given pathogen and guides the selection of effective therapy and the detection of resistance. Broth microdilution is widely regarded as a reference method and is valued for its reproducibility and its ability to test many drugs and concentrations at once. The International Journal of Anesthesia, the OpenAccessPub journal hosting this page, publishes peer-reviewed, open-access research relevant to perioperative and clinical care. Related OpenAccessPub work has reported antimicrobial susceptibility testing, including in vitro activity of iclaprim against resistant Staphylococcus aureus and susceptibility patterns of carbapenem-resistant Klebsiella pneumoniae. This page gathers open-access scholarship relevant to broth microdilution and antimicrobial susceptibility testing.
Research published in this journal
4 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Growing Threat Increased Carbapenem-Resistance among Klebsiella pneumoniae; Antibiotic Susceptibility Pattern of Klebsiella pneumoniae in a Tertiary Care Hospital
In Vitro Activity of Iclaprim Against Methicillin-Resistant Staphylococcus aureus Nonsusceptible to Daptomycin, Linezolid or Vancomycin
The Development and Evaluation of A Multiplex Real-Time PCR Assay for the Detection of ESBL Genes in Urinary Tract Infections
How this research is being cited
The 4 articles above have been cited 18 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2024 · PLoS ONE
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Solomon O. Olorunleke et al. · 2024 · PLoS ONE
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2023 · Selçuk tıp dergisi/Selçuk Üniversitesi Tıp Fakültesi dergisi
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Fatimah E. Alquraishi et al. · 2022 · International Journal of Health Sciences
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Aya A. Al-Baz et al. · 2022 · The Egyptian Journal of Hospital Medicine
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2022 · JAC-Antimicrobial Resistance
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2022 ·
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P. Bidet et al. · 2022 · JAC-Antimicrobial Resistance
A sample of recent works citing this journal's research on Broth Microdilution, linking to each citing work.