症例報告
Acquired Haemophilia: A Case Report and Literature Review参考訳：後天性血友病：症例報告および文献レビュー
Caine Regan, A. Gatnash
South Tyneside and Sunderland NHS Trust
* 責任著者
要旨
Acquired haemophilia (AHA) is a rare coagulation disorder secondary to autoantibodies against coagulation factor, most commonly factor VIII with potential for life threatening bleeding episodes. We report a case of an 88-year-old female presenting with frank haematuria three weeks after catheter insertion. Her background was of Alzheimer’s Dementia, Asthma and Bullous Pemphigoid for which she was on low dose maintenance prednisolone (5mg). Laboratory tests showed haemoglobin 98g/dl and partial thromboplastin time (PTT) of 60s, with corrected prothrombin time 52s. Fibrinogen 5.39. As such coagulation factors were tested which revealed factor VIII of 0%. Her case was complicated by urinary tract sepsis, as such she was treated with oral prednisolone 60mg without immunosuppressive agent usage. A pan-CT scan revealed likely mesothelioma for which she declined further investigation. This case report will describe a rare presentation of AHA associated with bullous pemphigoid and mesothelioma, complicated by infection and frailty.
著者キーワード
- Acquired haemophilia
- immunosuppressive agent
- coagulation factor
- ページ
- 1–5
- 論文種別
- 症例報告
- 受付日
- 2025年12月26日
- 採択日
- 2026年1月24日
- 掲載日
- 2026年3月2日
- ライセンス
- CC BY 4.0
- アクセス
- オープンアクセス
この論文の引用方法
Caine Regan, A. Gatnash (2026). Acquired Haemophilia: A Case Report and Literature Review. Journal of Hematology and Oncology Research 5(1):1-5. https://doi.org/10.14302/issn.2372-6601.jhor-25-5938.