Journal of Parasite Research

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Parasite Research-Assessment of therapeutic efficacy to the antifolates-Edwin Too

Nigeria

Research officer,
Kenya Medical Research Institute,
Centre for Biotechnology Research and Development.

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Edwin Too

Address:

Kenya Medical Research Institute,
Centre for Biotechnology Research and Development.

Research Interests:

  • Assessment of therapeutic efficacy to the antifolates, artemisinin and non-artemisinin based combinations against falciparum malaria.
  • Molecular characterization and application of radionuclide techniques for the detection of drug-resistant malaria parasites.
  • Monitoring of antimalarial drug efficacy using quantitative assays, e.g nucleic acid sequence-based amplification (QT-NASBA) and RT-PCR.
  • Transmission dynamics studies post-artemisinin-based intervention.
  • Parasite population studies determining origin and dispersal mechanisms of resistant parasites.
  • Human population studies investigating protection to malaria disease and prevalence of some human immune genes and other phenotypic markers.
  • Diagnosis of malaria parasites.
  • In vitro screening of traditional medicines for antimalarial activity, towards bio-prospecting for antimalarial agents.

Biography:

Publications:

  1. Evaluation of Efficacy of Artemether Lumefantrine and Dihydro-Artemisinin Piperaquine in Clearance of Gametocytes in Uncomplicated Plasmodium Falciparum Malaria and Effectiveness of Microscopy and Rt-Pcr in Gametocytes Detection. 
  2. PfEMP1 DBLα Sequence Tags in Genomic DNA of P. falciparum Field Isolates from Two Malaria Endemic Sites in Kenya.
  3. In Vivo Anti-malarial Test of Essential Oil Extracted from Nigella sativa (L.) Seeds‟. The   Journal of Ethnopharmacology. Sabah O mar, Rahma U. Yusuf, Edwin Too. (2009).