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Effect of Solvent pH on Antioxidant and Phytochemical Activities of Mulhatti Aerial Parts (Glycyrrhiza glabra L.)

Abstract:

Medicinal plants have been used since the era of Vedic history for their health care system where herbal medicine has a long history of use. It is also a very popular medicinal plant belonging to the Leguminosae family and is commonly known as Mulhatti. It contains phytochemicals such as flavonoids, triterpene saponins and other constituents such as coumarins, sugars, amino acids, tannins, starch, choline, phytosterols etc. The present study was conducted for the estimation of phytochemicals (total phenols and flavonoids) and the evaluation of the total antioxidant capacity and DPPH free-radical scavenging activity in aqueous extracts of different pH (2, 4, 7 and 9) from aerial parts of Glycyrrhiza glabra L. The content of phenolic compounds was maximal at pH 7 (14.13 mg GAE/g) and flavonoids at pH 9 (4.90 mg CE/g) and the total antioxidant capacity was maximal at pH 9 (13.43...

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Serum Ferritin Level as a Prognostic Marker of 30 days In Hospital Mortality of Coronavirus Disease 2019 (COVID 19) Pneumonia at World Citi Medical Center: A Retrospective, Observational Cohort, Single Center Study

Abstract:

Introduction

The COVID-19 pandemic continues to affect a large swath of the global population. The Philippine records four hundred seventy-four thousand sixty-four (474, 064) confirmed COVID 19 cases since December 31 2020. The COVID 19 pandemic recently highlighted the role of systemic hyperferritenemia as a major cause of death. In this study, we were able to correlate the serum ferritin level and predict 30 day in hospital mortality in COVID 19 pneumonia.

Objective

The aim of the study is to investigate the correlation between serum ferritin level and disease mortality in COVID19 pneumonia with subset analysis on demographics and co-morbidities of patients with COVID 19 pneumonia.

Methodology</titl...</p> <a class="btn btn-primary blue-btn text-uppercase my-4" href="https://openaccesspub.org/international-journal-of-coronaviruses/article/1737">Read Article</a> </div> </div> <div class="col-md-6 mb-3 aos-item aos-init " data-aos="fade-up"> <!-- child-div --> <div class="article-section p-3"> <h4 class="article-title title-border pb-3"> Variant Trifurcation of the Ulnar Nerve in Guyon’s Canal of the Human Wrist: Case report </h4> <h4 class="article-title fw-700">Abstract:</h4> <p><abstract> <p>During routine dissection of the right hand of a 52-year-old Asian descent male cadaver in the Department of Anatomy at Jazan University-Faculty of Medicine, we observed an anatomical variation of the ulnar nerve (UN). There was a trifurcation of the nerve in the ulnar tunnel proximal to the pisiform bone. An awareness of such variation may be of great clinical importance despite the presence of trifurcation of the ulnar nerve, which does not usually cause symptoms but becomes important in the evaluation of entrapment neuropathy and during surgical and orthopedic interventions </p> </abstract>...</p> <a class="btn btn-primary blue-btn text-uppercase my-4" href="https://openaccesspub.org/international-journal-of-human-anatomy/article/1738">Read Article</a> </div> </div> <div class="col-md-6 mb-3 aos-item aos-init " data-aos="fade-up"> <!-- child-div --> <div class="article-section p-3"> <h4 class="article-title title-border pb-3"> Synthesis of 2-Chloro-2′-Deoxyadenosine (Cladribine) and New Purine Modified Analogues</h4> <h4 class="article-title fw-700">Abstract:</h4> <p><abstract> <p>Theefficient two-step synthesis of 2-chloro-2′-deoxyadenosine (cladribine) via the anion glycosylation of purine potassium salt with the glycosyl chloride in binary solvent mixtures is described. A new method for preparation of diprotected 2-chloro-6-fluoropurine 2′-deoxy-β- D-riboside was developed by treatment of the 2,6-dichloropurine precursor with diethylaminosulfur trifluoride (DAST). Novel N6-alkylated cladribine analogue was synthesized by amination of acylated 2,6-dihalogenopurine nucleosides. It was found that a mild hydrolysis reaction of acylated 2-chloro-6-fluoropurine 2′-deoxy-β-D-riboside gave rise to new purine hydroxylated nucleoside.</p> </abstract>...</p> <a class="btn btn-primary blue-btn text-uppercase my-4" href="https://openaccesspub.org/new-developments-in-chemistry/article/1732">Read Article</a> </div> </div> <div class="col-md-6 mb-3 aos-item aos-init " data-aos="fade-up"> <!-- child-div --> <div class="article-section p-3"> <h4 class="article-title title-border pb-3"> Malignant Transformation of a Neurofibroma</h4> <h4 class="article-title fw-700">Abstract:</h4> <p><abstract> <p>Malignant transformation of peripheral nerve sheath tumor (MPNST) may develop from a<bold> </bold>plexiform type of Neurofibromatosis 1 (NF1) or previously irradiated areas. Generally, MPNSTs occur in about 2% to 5% of neurofibromatosis patients. In this paper, we present a 58-year-old male patient with neurofibromatosis who developed MPNST of the eyelids and nasal area. The patient had<bold> </bold>a history of multiple excision biopsies for facial tumors in 22 years<bold> </bold>at different institutions, allegedly revealing neurofibromas on histopathological evaluation. A recent consult with the Otorhinolaryngology Service (ORL) prompted an excision biopsy with results consistent with neurofibroma. The mass recurred and enlarged even more rapidly compared to the previously excised tumor. The patient also developed four tumors on the eyelids hence the<bold> </bold>referral to Ophthalmology S...</p> <a class="btn btn-primary blue-btn text-uppercase my-4" href="https://openaccesspub.org/ophthalmic-science/article/1733">Read Article</a> </div> </div> <div class="col-md-6 mb-3 aos-item aos-init " data-aos="fade-up"> <!-- child-div --> <div class="article-section p-3"> <h4 class="article-title title-border pb-3"> Two Implant Mandibular Overdentures: Clinical and Laboratory Procedures </h4> <h4 class="article-title fw-700">Abstract:</h4> <p><abstract> <p>Edentulism is considered a poor health outcome and may compromise quality of life. Implant-supported overdentures provide a good opportunity for dentists to improve the quality of life and oral health. Atrophic mandible poses a significant challenge to successful oral rehabilitation with dental implants. The aim of this case report is to demonstrate the concept of immediate functional loading in the mandible using unsplinted implants to support a locator attachment supported overdenture.</p> </abstract>...</p> <a class="btn btn-primary blue-btn text-uppercase my-4" href="https://openaccesspub.org/dentistry-and-oral-implants/article/1875">Read Article</a> </div> </div> <div class="col-md-6 mb-3 aos-item aos-init " data-aos="fade-up"> <!-- child-div --> <div class="article-section p-3"> <h4 class="article-title title-border pb-3"> A Review of Attempts to Improve Cow Fertility Through Reproductive Management: Estrous Synchronisation </h4> <h4 class="article-title fw-700">Abstract:</h4> <p><abstract> <p>This review focused on the various methods for controlling estrous cycles in well-managed dairy cows. Because up to 70% of dairy cows may stay non-pregnant after an AI procedure, an effective approach for identifying and reinseminating open cows is essential for dairy herds to achieve optimal reproductive performance. Overall, well-managed dairy farms with effective estrus detection programs inseminate 50% or more of non-pregnant cows after behavioral estrus is detected. Cows not detected in estrus are admitted in a resynchronization of ovulation procedure to receive a timed AI (TAI) service to avoid a long interbreeding interval. In Egypt, a widely used program involves starting the Ovsynch protocol (GnRH-7 d-PGF2-56 h-GnRH-16 to 20 h-TAI) 32 days after an initial AI, regardless of pregnancy status. Previous studies have proven that there was no...</p> <a class="btn btn-primary blue-btn text-uppercase my-4" href="https://openaccesspub.org/veterinary-healthcare/article/1731">Read Article</a> </div> </div> <div class="col-md-6 mb-3 aos-item aos-init " data-aos="fade-up"> <!-- child-div --> <div class="article-section p-3"> <h4 class="article-title title-border pb-3"> A Theory on the Impact of Copper and Micronutrients Against COVID-19 in Humans </h4> <h4 class="article-title fw-700">Abstract:</h4> <p><abstract> <p>Copper (Cu) has a strong impact on the function of the immune system through several different pathways. These impacts include helping the function of monocytes, neutrophils, and macrophages, and enhancing Natural Killer cells’ activities. Cu also has a role in antimicrobial properties and inflammatory response. It is also important for IL-2 production and response, which is a component of adaptive immune cells. Additionally, Cu has multiple roles in both proliferation and differentiation of T cells and is involved in the production of antibodies. Cu deficiency can even lead to "increased viral virulence"<xref ref-type="bibr" rid="ridm1842443108">1</xref>. Copper has a long history of use in medicine, and has continued to be used for purification of water, including use in hospitals to prevent legionnaires disease. The CDC pre...</p> <a class="btn btn-primary blue-btn text-uppercase my-4" href="https://openaccesspub.org/international-journal-of-infection-prevention/article/1735">Read Article</a> </div> </div> <div class="col-md-6 mb-3 aos-item aos-init " data-aos="fade-up"> <!-- child-div --> <div class="article-section p-3"> <h4 class="article-title title-border pb-3"> Retracted Article</h4> <h4 class="article-title fw-700">Abstract:</h4> <p></p> <a class="btn btn-primary blue-btn text-uppercase my-4" href="https://openaccesspub.org/clinical-case-reports-and-images/article/1729">Read Article</a> </div> </div> <div class="col-md-6 mb-3 aos-item aos-init " data-aos="fade-up"> <!-- child-div --> <div class="article-section p-3"> <h4 class="article-title title-border pb-3"> A Long-Term Polydromic Function to Disentangle Personal Remittance, Migration and Employment in Agriculture in Order to Raise the GDP of the Donor aid Ratio in Five African Countries </h4> <h4 class="article-title fw-700">Abstract:</h4> <p><abstract> <p>Economic statistics concerning the quinquennial features of Agriculture employment (A), net Migration (M), Donor aid (D) and Personal remittances (P), available for over forty years from five West African countries have here been related to the GDP (G). The overall results of a multilinear regression (R<xref ref-type="bibr" rid="ridm1842048092">2</xref> 0.84) have confirmed that the GD ratio, which is an index of aid efficiency, is significantly and positively driven by the PD ratio (high P and low D - favorable) and the PA ratio (high P and low A - favorable), but negatively driven by the PG ratio ( a higher D efficiency is obtained for constant G and lower P). A higher migration flux corresponds to a non-significant rise in the GD ratio. The five countries are clustered, by means of a principal component analysis, into three types. 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