Recently Published Articles
Fractures of the Humeral Condyles in Children – A Review
Abstract:
The three most common elbow fractures classically reported in pediatric orthopedic literature are supracondylar (50–70%), lateral condylar (17–34%), and medial epicondylar fractures (10%). The mechanism of injury varies, but the most commonly described mechanism involves a fall on an outstretched hand with varus, valgus or rotational force or a combination thereof. The vectors of force and the degree of chondro-osseous development dictate the type of injury incurred. A review of the literature was conducted to see the most frequent injuries and complications.
Molecular Spectroscopy and Molecular Docking Studies on (E)-1-(4-Bromobenzylidene) Thiourea
Abstract:
The organic molecule (E)-1-(4-bromobenzylidene)thiourea (BBTU) have been synthesized and characterized using FT-IR and FT-Raman spectral studies. The quantum chemical calculations of BBTU have been studied using DFT/B3LYP/6-31G(d,p) level of theory. The stable conformer is identified by the potential energy surface scan. The complete vibrational assignments were performed on the basis of PED analysis with the help of SQM method. NBO analysis was carried out to explore the various conjucative/hyperconjucative interactions within the molecule and their second order stabilization energy. The NLO activity of BBTU is calculated and compared with the standard Urea molecule. The energies of the FMOs are used for the determination of global reactivity descriptors. The electrophilic and nucleophilic charge sites were identified by the molecular electrostatic potential mapped surface. The molecular docking of BBTU is carried out with the receptors of 3U2D and 1JIJ to screen...
Impacts of Cassava Mill Effluents in Nigeria
Abstract:
Cassava is the fourth largest staple food after rice, wheat and maize. Cassava is produced in the tropical and sub-tropical countries. Currently, the global production of cassava is about 215,436,496 tons. Out of these, Nigeria accounts for 20.3%, being the largest producing nation. During processing of cassava flour (Gari), three main wastes are generated including cassava mill effluents (CME), solid and gaseous emission. This paper reviews the impacts of CME in Nigeria. The study found that CME’s physicochemical quality often exceeds the limit for effluents discharge onto land and surface water as recommended by Federal Environmental Protection Agency (FEPA), Nigeria. CME alters the quality of soil and water with regard to physicochemical, heavy metal and microbial characteristics. CME can induce toxicological effects on the environments and its biota including humans, fisheries, flora and fauna. The impacts are mostly associated with physicochemical (viz: odo...
The Duration of the Alcohol Hangover
Abstract:
Previous research has focused primarily on the severity of the alcohol hangover. Much less is known about the duration of the alcohol hangover. The objective of this analysis was to examine the average duration of the alcohol hangover. N=811 Dutch students, aged 18-30 years old, completed a survey on alcohol consumption and their latest alcohol hangover. Overall hangover severity was reported for every two hours after waking up (starting 4am until midnight). Hangover duration was calculated from the moment of stopping alcohol consumption until the first time hangover severity scores reached zero.
Coupling of 3D Bio-printing with Organ-on-a-chip Technology Creates New Possibility for Biomimicry
Abstract:
Editorial reflects on pairing 3D bioprinting with organ-on-a-chip systems to build tissue models that feel closer to living organs. The author discusses how microfluidic chips can nourish printed constructs, acknowledges scale hurdles, and invites researchers to share practical experiments in drug testing and regenerative medicine.
β-Cell function in type 1 diabetes may not be as low as presumed
Abstract:
We aimed to evaluate β-cell function of type 1 diabetic patients (T1DP)s based on fasting and stimulated C-peptide levels. Study included 135 T1DPs and 31 healthy subjects. Fasting C-peptide levels were measured in healthy subjects and T1DPs. The Mixed-meal tolerance test (MMTT) was performed in T1DPs. Fasting and stimulated (90 minute post MMTT) C-peptide levels were measured via electrochemiluminescence assay. Two categorizations were made according to fasting (the first categorization ) and at 90th minute MMTT (the second categorization) C-peptide levels. For the first categorization; the groups were classified as follows: patients with undetectable ≤0.1ng/mL(group1); minimal 0.1-0.8ng/mL(group2); and sustained ≥0.8ng/mL (group3) C-peptide levels. For the second cate...
Experimental-Morphological Study of Reparative Bone Formation with The Replacement of The Cavity Defect of The Bone with A Mesh of Titanium Nickelide
Abstract:
To study reparative osteogenesis and tissue integration characteristics for implanting three-dimensional mesh structures of titanium nickelide into a bone cavitary defect. The authors modeled cavitary defects of femoral metaphysis experimentally in Wistar rats divided into an experimental group and control one. The study duration was 60 days in total. The methods of radiography, those of light and electron microscopy, X-ray electron probe microanalysis used. Under implantation the defect was filled with cancellous bone the volumetric density of which more than 1,5-fold exceeded control values (р < 0.001). The implant had biocompatibility, osteoconductive and osteoinductive proper...
Social Capital and Health Outcomes of Elderly People
Abstract:
Greater social capital has been shown to be associated with improved mental health, general wellbeing and reduced risk of premature mortality, cancer mortality and cardiovascular mortality. However, most of these studies found a positive relationship between social capital and health are limited to descriptive studies. This project is performing a theoretical approach to the role of social capital in producing health outcome based on Becker’s household production function. We are testing whether social capital has a positive impact on health both directly through a more effective production of health and indirectly through utilizing the health care system better, using several measurements of social capital from ‘social support’ module in the National Health and Nutrition Examination Survey (NHANES) 2007-2008 for a sample of those 60 years old and above. NHANES is a unique data set in terms of collecting both subjective self-rated health statu...
Perception Threshold Variations of Pain Area with Herpetic Ophthalmic Neuralgia
Abstract:
To measure the affected subepidermal nerve sensation with a combination of current perception threshold (CPT) and Semmes-Weinstein monofilament (SWM) testing under pain areas with herpetic ophthalmic neuralgia (HON). One hundred fifty-five subjects with HON and 30 age-matched volunteers were recruited for the study. The combined SWM and CPT testing yielded significantly abnormal responses at the painful sites for the patients with HON compared to those responses of the normal controls (
International Journal of Chemotherapy and Practice; A Novel Journal for Therapeutic Researches
Abstract:
An inaugural editorial presents the journal's scope spanning chemotherapy research and clinical practice. It invites translational work linking mechanisms, regimens, and real‑world outcomes with an emphasis on safety and effectiveness.