Journal of Neurological Research and Therapy

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Aims and Scope

What the journal publishes

Journal of Neurological Research and Therapy · ISSN 2470-5020

Basic, clinical, applied, experimental and translational research in neuroscience and neurology, from molecular and cellular mechanisms to clinical care and rehabilitation.

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Our aim

Neuroscience and neurology research, from mechanism to clinical care

The Journal of Neurological Research and Therapy welcomes basic, clinical, applied, experimental and translational research that advances understanding of the nervous system and neurological disorders, including their prevention, diagnosis, treatment and rehabilitation. Coverage includes molecular, cellular, systems and computational neuroscience; laboratory and animal-model investigations; clinical studies; neuroimaging; neurotechnology; therapeutics; and rehabilitation. The journal aims to connect fundamental understanding of the nervous system with advances in neurological disease prevention, diagnosis, treatment and rehabilitation, and gives that work a citable, open-access route to the researchers and clinicians who use it.

Eligibility. Basic and experimental studies are eligible without an immediate clinical application, provided they address a clear neuroscience or neurological question with appropriate scientific methods.

Scope check

Is your study in scope?

The lists below summarize work that is in scope and work that falls outside it.

In scope

  • Basic, clinical, applied, experimental and translational research in neuroscience and neurology
  • Molecular, cellular, systems and computational neuroscience; animal-model, laboratory, in-vitro and computational studies that address a clear neuroscience or neurological question, with or without an immediate clinical application
  • Clinical studies in areas including epilepsy, neurodegeneration (ALS and motor neuron disease, Parkinson's disease, dementia and Alzheimer's disease), multiple sclerosis and neuroimmunology, stroke and neurovascular disease, neurotrauma and neurocritical care, neuro-oncology, pediatric neurology and clinical neurophysiology
  • Neuroimaging, neurotechnology, therapeutics and rehabilitation

Out of scope

  • Topics with no neuroscience or neurological question, for example general internal medicine, oncology or cardiology without a nervous-system focus. Work in which the neuroscience or neurological question is central and documented may fit.
  • Sports and exercise science without a neuroscience or neurological question. Work on neurotrauma or concussion with a clear neurological question is in scope.
  • Unsupported opinion: viewpoints not grounded in cited evidence, data or a documented clinical case. Evidence-grounded Perspectives, Commentaries and Letters to the Editor are welcome; see the Instructions for Authors for their requirements.
Research categories

The work we publish

These research categories describe what the work is about; they illustrate the scope rather than limit it. Each “typical fit” shows the kind of work we welcome.

Basic and Computational Neuroscience

  • Molecular and cellular neuroscience
  • Systems and computational neuroscience
  • Laboratory and animal-model investigations
  • In-vitro and computational models of neural function
Typical fitA cellular or animal-model study of a synaptic, glial or circuit mechanism, or a computational model of neural activity, that addresses a clear neuroscience question, whether or not it has an immediate clinical application.

Epilepsy and Seizure Disorders

  • Antiepileptic drug therapy and treatment response
  • Drug-resistant and refractory epilepsy
  • EEG and seizure semiology
  • Epilepsy in special populations
Typical fitA clinical study of treatment response to a new antiepileptic regimen in drug-resistant focal epilepsy, an experimental study of seizure mechanisms in an animal or cellular model, or an EEG study of seizure semiology in a defined patient cohort.

Neurodegeneration

  • ALS and motor neuron disease
  • Parkinson's disease and movement disorders
  • Dementia and Alzheimer's disease
  • Disease biomarkers and progression
Typical fitA cohort study of disease progression or a candidate biomarker in Parkinson's disease, a cellular or animal-model study of a neurodegenerative mechanism, or a clinical study comparing atypical parkinsonian or motor neuron disease phenotypes.

Multiple Sclerosis and Neuroimmunology

  • Multiple sclerosis diagnosis and management
  • Disease-modifying therapy outcomes
  • Neuroinflammation and autoimmune neurology
  • Immune biomarkers
Typical fitA study of disease-modifying therapy outcomes in relapsing multiple sclerosis, or a report on an autoimmune or paraneoplastic neurological syndrome.

Stroke and Cerebrovascular Disease

  • Acute ischemic and hemorrhagic stroke
  • Reperfusion and secondary prevention
  • Cerebrovascular imaging and risk
  • Post-stroke recovery
Typical fitA clinical study of reperfusion or secondary-prevention outcomes after ischemic stroke, or a neurovascular imaging analysis tied to a clinical question.

Neurotrauma and Neurocritical Care

  • Traumatic brain and spinal cord injury
  • Neurocritical care management
  • Intracranial pressure and monitoring
  • Outcome prediction
Typical fitA study of management or outcomes in traumatic brain injury, or a neurocritical-care protocol evaluation with patient outcomes.

Clinical Neurophysiology and Neurotechnology

  • EEG, EMG and evoked-potential studies
  • Electrophysiology of neural function
  • Neurotechnology for recording and monitoring neural function
  • Diagnostic methods in neurology
Typical fitA clinical neurophysiology study tied to a diagnosis, an evaluation of a neurotechnology for recording or monitoring neural function, or a diagnostic-accuracy study of an electrophysiological method in a defined neurological population.

Neuroimaging, Therapeutics and Rehabilitation

  • Structural and functional neuroimaging
  • Neuropharmacology and therapeutic development
  • Prevention and treatment of neurological disorders
  • Neurorehabilitation and functional recovery
Typical fitA neuroimaging study of brain structure or function that addresses a neurological question, a preclinical or clinical evaluation of a therapy, or a rehabilitation study with functional outcomes.

Neuro-oncology

  • Primary brain and spinal cord tumors
  • Brain metastases and neurological complications of cancer
  • Neurological effects of cancer therapy
  • Imaging, biomarkers and outcomes in neuro-oncology
Typical fitA clinical or experimental study of a primary brain tumor or of the neurological effects of cancer treatment that addresses a clear neurological question.

Pediatric Neurology

  • Childhood epilepsy and seizure disorders
  • Neurodevelopmental and genetic neurological disorders
  • Pediatric neuromuscular disease
  • Neonatal neurology
Typical fitA clinical study of diagnosis, treatment or outcomes in a childhood neurological disorder, or a genetic or neurodevelopmental study of a rare pediatric neurological disorder.

Article formats are separate from the research categories above: Original research, Review, Systematic review and meta-analysis, Case report (including short case series), Short communication, Brief report, Study protocol, Methodology, Perspective, Letter to the Editor and Commentary. Editorials are commissioned by the editors. For how to prepare each format, see the Instructions for Authors.

Publishing with JNRT

Review, access and charges

JNRT is a peer-reviewed, open-access journal for basic, clinical, applied, experimental and translational research in neuroscience and neurology.

Editorial board

Manuscripts are handled by subject-expert editors in neuroscience and neurology, supported by an international board of clinicians and researchers.

Peer review

Single-blind by default; double-blind review is available on request. Manuscripts that proceed to external peer review are normally evaluated by at least two independent subject-matter experts.

Open access with a DOI

Articles are published open access under a Creative Commons Attribution (CC BY) license, each with a permanent Crossref DOI.

Case reports

Well-documented neurological case reports, including short case series, are welcome when they carry clear, generalizable learning.

Editorial screening

Each submission is acknowledged and screened by the editorial office before peer review.

Article processing charge

A single article processing charge of USD 2,100 is payable only after acceptance; withdrawal after submission is subject to the journal's withdrawal policy. There is no fee to submit or to be reviewed.

See article processing charges

Pre-submission inquiries

Send a working title and short abstract, and the editorial office will advise whether your study is in scope before you prepare a full submission.

Ask a pre-submission question
Scope questions

Frequently asked

How do I know if my study is in scope?
If your work addresses a clear neuroscience or neurological question with appropriate scientific methods, whether it is basic, clinical, applied, experimental or translational, it is likely to be in scope. The in-scope and out-of-scope lists above are the quickest guide.
What subjects does the journal cover?
Basic, clinical, applied, experimental and translational research that advances understanding of the nervous system and neurological disorders, including molecular, cellular, systems and computational neuroscience; laboratory and animal-model investigations; clinical studies; neuroimaging; neurotechnology; therapeutics; and rehabilitation. Clinical areas include, for example, epilepsy, neurodegeneration (ALS and motor neuron disease, Parkinson's disease, dementia and Alzheimer's disease), multiple sclerosis and neuroimmunology, stroke and neurovascular disease, neurotrauma and neurocritical care, neuro-oncology, pediatric neurology and clinical neurophysiology.
Do you publish case reports?
Yes. Case report is one of the journal's article formats, and a short case series is submitted and classified as a case report. The strongest reports carry clear, generalizable learning, with imaging, workup and outcome documented and patient consent, or a documented waiver where applicable.
Do you accept animal, laboratory, in-vitro or computational studies?
Yes. Animal-model, laboratory, in-vitro and computational studies are in scope when they address a clear neuroscience or neurological question with appropriate scientific methods, as set out under Eligibility above. Animal studies require approval from an institutional animal care and use committee or animal ethics committee, compliance with applicable national and institutional animal-welfare regulations and the 3Rs, and reporting in line with the ARRIVE guidelines; see the editorial policies.
Are systematic reviews and meta-analyses welcome?
Yes. Rigorous systematic reviews and meta-analyses on neuroscience and neurological topics are welcome. Systematic review and meta-analysis is one of the journal's article formats (see the article formats listed above).
Do you publish clinical trials, and is registration required?
Yes. Interventional clinical trials must be registered in an accepted public trial registry at or before the first participant provides consent for enrollment. The registry name, registration number, and registration date must be reported in the manuscript.
Is stroke and neurovascular research in scope?
Yes. Acute ischemic and hemorrhagic stroke, reperfusion and secondary prevention, cerebrovascular imaging and risk, and post-stroke recovery are all in scope, whether the work is basic, clinical, applied, experimental or translational.
Do you consider neurodegeneration research (ALS, Parkinson's disease, dementia)?
Yes. Neurodegeneration is one of the journal's research categories, including ALS and motor neuron disease, Parkinson's and other movement disorders, and dementia and Alzheimer's disease, from cellular and animal-model mechanisms, biomarkers and progression to therapy.
Are multiple sclerosis and neuroimmunology in scope?
Yes. Multiple sclerosis diagnosis and management, disease-modifying therapy outcomes, neuroinflammation and autoimmune neurology are all welcome.
Do you cover clinical neurophysiology?
Yes. EEG, EMG and evoked-potential studies, and the electrophysiology of neural function, are in scope when they address a clear neuroscience or neurological question.
What about neurotrauma and neurocritical care?
Yes. Traumatic brain and spinal cord injury, neurocritical-care management, intracranial-pressure monitoring and outcome prediction are in scope.
Are neuro-oncology and pediatric neurology in scope?
Yes. Neuro-oncology and pediatric neurology are in scope, from basic and experimental studies to clinical care, when the work addresses a clear neuroscience or neurological question.
Do you publish Perspectives, Commentaries and Letters?
Yes. Perspective, Commentary and Letter to the Editor are accepted article formats. They do not need original data, but they must present an argument grounded in cited evidence, with conclusions proportionate to that evidence. Unsupported opinion is out of scope.
Are null or negative results considered?
Yes. Well-designed studies are judged on rigor and relevance, not on the direction of their findings. Robust null or negative results that inform neuroscience or neurology are welcome.
Is sports or performance science in scope?
Only when it poses a clear neuroscience or neurological question, for example concussion or neurotrauma. General sports and exercise science without that focus is out of scope.
I am not sure my topic fits. Can I check first?
Yes. We welcome pre-submission inquiries. Email a working title and short abstract to the editorial office, which will advise whether your study is in scope before you prepare a full submission.

Submitting to JNRT

If your research advances understanding of the nervous system or neurological disorders, read the author guidelines and submit through ManuscriptZone, or ask us first if you are unsure.

Submit Manuscript Instructions for Authors Editorial board

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