- Open access · CC BY 4.0
- ISSN 2572-5424 (online)
- Published by Open Access Pub
Aims and Scope
The Journal of Glycomics and Metabolism publishes research on glycans and metabolism, from molecule to organism, including the molecular mechanisms of glycosylation and metabolic disorders.
What the journal sets out to do
- To publish rigorous research on how glycans and glycoconjugates are built, recognized and degraded, and on the metabolic networks that connect them.
- To report the molecular, cellular and physiological mechanisms of glycosylation and metabolic disorders.
- To advance the analytical, experimental and computational methods on which glycomics and metabolic research depend.
- To make this research openly available, so that researchers, clinicians and educators can read and reuse it freely.
Research areas
The journal considers research on any aspect of glycan biology and metabolism. The areas below are illustrative and form part of a wider field.
Glycan structure and biosynthesis
Glycosyltransferases and glycosidases, N- and O-glycan assembly, and nucleotide-sugar metabolism.
Glycoproteins and glycoproteomics
Site-specific glycosylation, glycoprotein folding and quality control, and post-translational crosstalk.
Glycan recognition
Lectins, glycosaminoglycans and carbohydrate-binding proteins in signaling and host-microbe interactions.
Metabolic pathways and regulation
Carbohydrate, lipid and amino acid metabolism, nutrient sensing and metabolic flux.
Analytical and computational methods
Mass spectrometry, NMR, glycan arrays, metabolomics, isotope tracing and glycoinformatics.
Glycosylation and metabolic disorders
Molecular mechanisms of congenital disorders of glycosylation, inborn errors of metabolism and metabolic syndrome.
Further topics
- Glycan biosynthesis, processing and degradation
- Glycosyltransferases, glycosidases and nucleotide-sugar metabolism
- N-glycans, O-glycans and glycosphingolipids
- Glycosaminoglycans and proteoglycans
- Glycoproteomics and site-specific glycosylation
- Lectins and glycan-recognition proteins
- Glycans in cell signaling, immunity and host-microbe interaction
- Carbohydrate metabolism and glucose homeostasis
- Lipid and lipoprotein metabolism
- Amino acid and nitrogen metabolism
- Mitochondrial and energy metabolism
- Nutrient sensing and metabolic regulation
- Metabolomics, lipidomics and isotope tracing
- Glycomics, glycoinformatics and computational modeling
- Congenital disorders of glycosylation
- Inborn errors of metabolism
- Metabolic syndrome, diabetes and obesity
- Microbiome and metabolism
- Nutrition and metabolic health
- Glycan and metabolite analysis by mass spectrometry and NMR
Contributions from chemistry, biochemistry, cell and molecular biology, physiology, nutrition, microbiology, analytical science, bioinformatics and clinical research are welcome when they address a question about glycans or metabolism. A topic that is not named above is within scope when it meets that test.
Study systems and approaches welcomed
JGM considers laboratory, computational, clinical and population research, alone or combined. Study designs are reported within the article types listed below.
Molecular and biochemical
Enzyme mechanism, structure, glycan and metabolite chemistry, and in vitro reconstitution.
Cellular and model organisms
Cell culture, animal models, microbes and plants, including genetic and pharmacological manipulation of glycosylation or metabolic pathways.
Analytical and computational
Mass spectrometry, NMR, glycan arrays, metabolomics, isotope tracing, glycoinformatics and modeling.
Human and clinical
Studies of human samples, cohorts and clinical cases that address the mechanisms of glycosylation or metabolic disorders and their care.
What makes a manuscript a fit
Manuscripts are assessed for their relevance to glycans or metabolism, the soundness of their methods and whether their conclusions are proportionate to the evidence. Basic, translational and clinical work are all considered.
Case Reports
Case Reports, including short case series, are accepted when the case carries a lesson for diagnosis, mechanism or care, such as a metabolic or glycosylation disorder with an unusual presentation.
Perspectives and Letters
Perspectives and Letters are accepted when they make a reasoned argument, supported by evidence and cited sources, on a question in the field or on work published in JGM. Unsupported opinion, meaning assertion without evidence or reasoned argument, is outside the journal's scope.
Research involving humans or animals
Research involving human participants or animals follows the requirements in the Editorial Policies and is reported following the guideline that matches its design, for example STROBE, CONSORT, ARRIVE or MIRAGE, where applicable.
Data
Every empirical research manuscript includes a data-availability statement. Deposit of glycomic, glycoproteomic, metabolomic and structural data in recognized public repositories is encouraged. See Data Archiving and Permissions.
Article types
The journal publishes the article types below.
- Original ResearchEmpirical studies of glycans, glycoconjugates or metabolism, from molecular and cellular work to studies of tissues, organisms and populations.
- ReviewNarrative, scoping or systematic reviews of a defined question in glycan biology or metabolism. A systematic review is submitted as a Review.
- Methods and ProtocolsNew, adapted or validated methods, analytical and computational tools, and protocols for planned studies.
- Short CommunicationConcise reports of a focused or preliminary finding.
- Data NoteDescriptions of datasets, such as glycomic, glycoproteomic or metabolomic data, to support their reuse.
- Case ReportIndividual cases or short case series, such as a metabolic or glycosylation disorder, that carry a lesson for diagnosis, mechanism or care. A case series is submitted as a Case Report.
- PerspectiveReasoned, evidence-based argument on a current question in the field or on published work.
- LetterBrief responses to articles published in the journal, or short observations of relevance to the field.
Where a manuscript sits between types, authors choose the closest type and explain the choice in the cover letter, and the editors confirm the classification. A systematic review is classified as a Review, a short case series as a Case Report, and a study protocol as Methods and Protocols.
Guidance on the structure, abstract and reporting standard for each type is given in the Instructions for Authors.
Scope questions
Is my topic within scope?
A manuscript is within scope when it addresses a question about glycans or metabolism, whatever its discipline or setting. If you are unsure, send the title and abstract to the editorial office at [email protected] before submitting.
Are clinical studies and case reports within scope?
Yes, when they address the mechanisms, diagnosis or care of glycosylation or metabolic disorders or other questions about glycans and metabolism.
Can I submit work that has been posted as a preprint?
Yes. Posting a preprint is compatible with submission. Cite the preprint and its DOI in the cover letter.
Does the journal consider chemical or analytical work?
Yes. New methods for the synthesis, analysis or computational study of glycans and metabolites are considered as Methods and Protocols or Original Research.
Preparing a submission
Read the Instructions for Authors and the Editorial Policies before submitting.