Research Topic · Peer-Reviewed

Arthritis

Arthritis denotes inflammation of one or more joints, producing pain, swelling, stiffness, and restricted movement, and encompasses a heterogeneous group of conditions with distinct pathophysiology. Osteoarthritis arises from progressive degradation of articular cartilage and subchondral bone, whereas inflammatory a…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 37× across the literature 🗓 Reviewed June 2026

Overview

Arthritis denotes inflammation of one or more joints, producing pain, swelling, stiffness, and restricted movement, and encompasses a heterogeneous group of conditions with distinct pathophysiology. Osteoarthritis arises from progressive degradation of articular cartilage and subchondral bone, whereas inflammatory and autoimmune forms such as rheumatoid arthritis and the juvenile idiopathic arthritides are driven by immune-mediated synovial inflammation, with septic arthritis resulting from direct joint infection. The synovium is a central site of disease, where pannus formation, cellular infiltration, and altered megakaryocyte and cartilage biology contribute to joint destruction; genetic susceptibility, including transcription-factor variants such as STAT4, modulates risk in several autoimmune arthritides. Diagnosis integrates clinical examination, imaging, and laboratory markers, while management ranges from physical and pharmacological therapy to targeted agents and, in complications, surgical intervention. The peer-reviewed studies indexed under this topic include case series of juvenile idiopathic arthritis, iatrogenic extra-capsular spread of septic arthritis, synovial megakaryocyte changes in arthritic joints, a controlled trial in knee arthritis, and analyses of disease-associated genetic regulation, alongside drug-related ocular complications of antirheumatic therapy. Collectively they reflect investigation spanning the epidemiology, pathology, genetics, and treatment of arthritic disease across pediatric and adult populations.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 37 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Arthritis, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Bone Marrow Biology.

Journal editorial board
Azad Saei · Sweden Shanmuganathan Chandrakasan · United States Sadanand Fulzele · United States

This page summarises published research for orientation; it is not medical or professional advice.