Overview
Oxygen is the diatomic element (O2) essential for aerobic life, serving as the terminal electron acceptor in mitochondrial respiration and thereby underpinning efficient energy production. Its electronic structure makes it both indispensable and potentially hazardous, because partial reduction of molecular oxygen generates reactive oxygen species such as the superoxide anion radical, hydrogen peroxide, and the hydroxyl radical, while related forms including singlet oxygen and ozone are still more reactive. These species participate in signalling and host defence at controlled levels but cause oxidative damage to lipids, proteins, and nucleic acids when their generation outpaces antioxidant defences, a state termed oxidative stress that is implicated in ageing, ischaemia-reperfusion injury, and metabolic and degenerative disease. Measurement of oxygen status, reactive intermediates, and antioxidant capacity is therefore central to redox biology. Research published in this area by the journal examines oxygen and its reactive derivatives in this light, including the oxidative effects of ozone and oxygen on testicular mitochondria, antioxidative protection of sperm mitochondria by ozone therapy, non-enzymatic formation of methylglyoxal and superoxide during glycation, radical-scavenging and antioxidative activities in cardiomyoblast cells, regulation of reactive oxygen intermediates during malaria infection, and alveolar-arterial oxygen gradients in respiratory disease. These contributions span free-radical biochemistry, oxidative stress, and the assessment of antioxidant and oxygen-related processes.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Antioxidative Protective Effect of Ozone Therapy on Isolated Mitochondria from Human Sperm
The Potentials of Antioxidant Micronutrients in the Management of Metabolic Syndrome
Non-Enzymatic Methylglyoxal Formation From glucose Metabolites and Generation of Superoxide Anion Radical During Methylglyoxal-Dependent Cross-Links Reaction
Can Alveolar-Arterial Oxygen Pressure Difference be used to Diagnose Acute Respiratory Distress Syndrome in Pneumonia Patients?
Investigation of Edge-Selectively Nitrogen-Doped Metal Free Graphene for Oxygen Reduction Reaction
Regulation of Expression of Reactive Oxygen Intermediates During Plasmodium Infection to Reduce Immunopathology Provides a Possible Antioxidant Adjuvant to Enhance Anti-Malarial Drug Therapy
Radical-Scavenging and Anti-Oxidative Activities of TBN in Cell-Free System and Murine H9c2 Cardiomyoblast Cells
The antioxidant and hepatoprotective activities of two tea polysaccharides
Antioxidant Activity of Surinamese Medicinal Plants with Adaptogenic Properties and Correlation with Total Phenolic Contents
Antioxidant Activity of Pod Coat Extracts of Pigeon Pea (Cajanus Cajan L.) and Their Efficacy in Stabilization of Soybean Oil
How this research is being cited
The 12 articles above have been cited 98 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Russian Military Medical Academy Reports
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2025 · International Journal of Biological Macromolecules
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2025 · Faculty of Natural and Applied Sciences Journal of Applied and Physical Sciences
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Mukhtar Gambo Lawal et al. · 2025 · Experimental parasitology
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2025 · Experimental Parasitology
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2025 · Legume Science
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2025 · Antioxidants
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2025 · Chemical Engineering Journal
A sample of recent works citing this journal's research on Oxygen, linking to each citing work.