Oxidative stress is a state of imbalance in which the production of reactive oxygen species exceeds the body's capacity to neutralise them with antioxidants, leading to damage of cellular components such as lipids, proteins, and DNA. Reactive oxygen species are generated as a normal by-product of metabolism, but whe…
Oxidative stress is a state of imbalance in which the production of reactive oxygen species exceeds the body's capacity to neutralise them with antioxidants, leading to damage of cellular components such as lipids, proteins, and DNA. Reactive oxygen species are generated as a normal by-product of metabolism, but when their levels are not adequately controlled they can disrupt cell function and contribute to disease. Oxidative stress is implicated in cardiovascular disease, diabetes, cancer, ageing, and neurodegenerative conditions. The body counters reactive species through enzymatic and non-enzymatic antioxidant defences, and research examines both the mechanisms by which oxidative damage occurs and the protective potential of dietary and therapeutic antioxidants. Studies frequently use cell-based and animal models to probe oxidative injury in tissues and to evaluate compounds that may mitigate it. The journal publishes peer-reviewed work relevant to these themes, including antioxidant micronutrients in metabolic syndrome, oxidative stress and apoptosis induced by lipopolysaccharide in testicular tissue, the cytoprotective effects of resveratrol against hydrogen-peroxide-induced injury in astrocytes, quercetin's attenuation of manganese-induced neurotoxicity, the protective effect of buspirone against liver oxidative stress, methylglyoxal-related radical formation, and antioxidant phytochemicals as potential treatments for age-related macular degeneration, situating oxidative stress within the broader study of Antioxidant Activity.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 115 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Oxidative Stress, linking to each citing work.