Research Topic · Peer-Reviewed

Antioxidants in Cardiovascular Health

Antioxidants in cardiovascular health refers to the study of how compounds that neutralize reactive oxygen species influence the development and progression of disorders affecting the heart and blood vessels. Oxidative stress is central to vascular pathology: excess free radicals oxidize low-density lipoprotein, imp…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 85× across the literature 🔖 ISSN 2471-2140 🗓 Reviewed June 2026

Overview

Antioxidants in cardiovascular health refers to the study of how compounds that neutralize reactive oxygen species influence the development and progression of disorders affecting the heart and blood vessels. Oxidative stress is central to vascular pathology: excess free radicals oxidize low-density lipoprotein, impair nitric-oxide-dependent vasodilation, and promote endothelial dysfunction, foam-cell formation, and the chronic inflammation underlying atherosclerosis. Antioxidant defenses counter these processes through enzymatic systems such as superoxide dismutase, catalase, and glutathione peroxidase, alongside dietary and phytochemical compounds including vitamins C and E, carotenoids, and polyphenols such as flavonoids and phenolic acids. Research in this area examines how these molecules modulate lipid peroxidation, redox signaling, and inflammatory pathways relevant to hypertension, ischemia-reperfusion injury, and metabolic risk factors. Investigators commonly characterize antioxidant capacity using assays of total antioxidant status, radical-scavenging activity, and total phenolic content, often relating chemical potency to physiological outcomes in cellular and animal models. A recurring scholarly question is the gap between strong in vitro and preclinical antioxidant effects and the more variable results of human supplementation trials, which has shifted emphasis toward dietary patterns, bioavailability, and the distinction between physiological redox regulation and indiscriminate radical removal in protecting cardiovascular tissue.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2017

The antioxidant and hepatoprotective activities of two tea polysaccharides

Yu ZhiCorresponding author
College of Horticulture and Forestry Science, Huazhong Agricultural University, Key Laboratory of Horticultural Plant Biology, Ministry of Education, No. 1 Shizishan Street, Hongshan District, Wuhan City, Hubei Province, China 430070
Antioxidant Activity Cited by 5 doi:10.14302/issn.2471-2140.jaa-17-1541

How this research is being cited

The 12 articles above have been cited 85 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Antioxidants in Cardiovascular Health, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Antioxidant Activity (ISSN 2471-2140).

Journal editorial board
Deepak Kasote · Qatar Mahmoudreza Ovissipour · United States Sudhiranjan Gupta, Ph.D. · United States

This page summarises published research for orientation; it is not medical or professional advice.