Research Topic · Peer-Reviewed

Antioxidants and Chemical Toxicity

Antioxidants are molecules that inhibit the oxidation of other compounds by neutralizing reactive oxygen and nitrogen species, and the study of antioxidants in chemical toxicity examines how these protective agents counter the oxidative damage that toxicants inflict on cells, tissues, and biomolecules. Many environm…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 78× across the literature 🔖 ISSN 2471-2140 🗓 Reviewed July 2026

Overview

Antioxidants are molecules that inhibit the oxidation of other compounds by neutralizing reactive oxygen and nitrogen species, and the study of antioxidants in chemical toxicity examines how these protective agents counter the oxidative damage that toxicants inflict on cells, tissues, and biomolecules. Many environmental and dietary toxicants act, at least in part, by generating free radicals that attack lipids, proteins, and DNA, producing oxidative stress that underlies hepatotoxicity, mutagenicity, and tissue injury. Antioxidants intervene through several mechanisms: direct radical scavenging, metal chelation, enzyme induction, and restoration of endogenous defenses such as glutathione and catalase. Research in this area characterizes natural and dietary antioxidants, frequently plant-derived phenolics, flavonoids, and polysaccharides, and evaluates their capacity to reduce toxicant-induced harm. Representative work assesses total antioxidant capacity of foods and extracts, phytochemical screening of medicinal plants, and protective effects against aflatoxin exposure and chemically induced oxidative stress. Hepatoprotective activity is a recurring endpoint, reflecting the liver's central role in detoxification. Other lines of inquiry consider antioxidant stabilization of edible oils and the relationship between phenolic content and protective potency. Collectively, the field links antioxidant chemistry to mitigation of chemical toxicity across nutritional, pharmacological, and environmental contexts.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2017

The antioxidant and hepatoprotective activities of two tea polysaccharides

Yu ZhiCorresponding author
College of Horticulture and Forestry Science, Huazhong Agricultural University, Key Laboratory of Horticultural Plant Biology, Ministry of Education, No. 1 Shizishan Street, Hongshan District, Wuhan City, Hubei Province, China 430070
Antioxidant Activity Cited by 5 doi:10.14302/issn.2471-2140.jaa-17-1541

How this research is being cited

The 12 articles above have been cited 78 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Antioxidants and Chemical Toxicity, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Antioxidant Activity (ISSN 2471-2140).

Journal editorial board
Deepak Kasote · Qatar Mahmoudreza Ovissipour · United States Sudhiranjan Gupta, Ph.D. · United States

This page summarises published research for orientation; it is not medical or professional advice.