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Evolutionary Conservation of Hox Genes in Vertebrate Brain Development

Abstract:

Hox genes, their conserved derivatives, and the pathways responsible for their expression have been extensively studied in the fruit fly, Drosophila melanogaster;the experimentation done in the Drosophila model system has given developmental biologists tools to better understand the role and significance of Hox genes and their derivatives in anterior-posterior axis determination in the Drosophila embryo. Along with this, Drosophila research opened up the door to investigation on the conservation of Hox genes between vertebrates and invertebrates. Comparative embryology in mice, chickens, pufferfish, and zebrafish have shown conserved Hox gene expression patterns specifically along the anterior-posterior axis. Recently, comparative analysis performed on dorsal-ventral axis formation showed that patterning and segmentation of the sp...

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Healthy Aging and Muscle Dysfunction: Will Melatonin Help?

Abstract:

Background

Aging is said to represent a declining state that is possibly especially compromised by sleep issues, and declining melatonin levels.

Aim

This review examined the idea that aging can be favorably influenced in numerous ways by the addition or maintenance of adequate melatonin levels. Specifically, the impact of melatonin on skeletal muscle was the key topic of interest.

Method

Reviewed were peer reviewed research and review articles specifically pertaining to healthy aging, melatonin, and muscle associated observations.

Results

Declining melatonin levels greatly impact multiple essential body systems and tissues. Supplements or ...

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“Happy Village” Concept Helping Villages to Face COVID-19

Abstract:

“Health Promoting Village” concept named as “Happy Villages” started in 2007 in Badulla District in Uva Province was a community mobilization process through which village communities have been empowered to look after their community health. The areas included were Early Childhood Care and Development (ECCD), Non-Communicable Diseases (NCD) prevention , Alcohol and drug abuse. Gender Based Violence. The programmed used many interactive tools as “Mood Chart” or “Happiness Calendar” which was giving a visualizing effect. Continuous assessments done from 2009 to 2013 showed that the Health promotion strategies used in the Happy Village concept in the Uva Province can effectively and efficiently be utilized for improvement of nutrition and achievement of milestones in children. From 2017 a National program is launched named “Happy Villages”. During the Covid 19 outbreak health promotion approaches were initiated to change in ...

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Antimicrobial Resistance: A Situational Analysis in the Deido Health District, Douala, Cameroon

Abstract:

Background

The rapid and ongoing spread of antimicrobial-resistant organisms threatens the ability to successfully prevent, control, or treat a growing number of infectious diseases in developed and developing countries. This study was designed to convey more insight on the profile of antimicrobial resistance and the capacity of laboratories conducting antimicrobial susceptibility testing in Cameroon.

Methods

A multicentre cross-sectional study was conducted from October 2019 to March 2020 in the Deido Health District. Laboratories that carry out culture and sensitivity testing within the Deido Health District were identified and assessed to determine their capacity as well as the quality of results from microbiological investigations. Information on antimicrobial susceptibility of various isolates was collected usi...

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Insecticidal Activity of Cyperus rotundus L. and Datura stramonium L. Co-Administered with Sesame Oil Against African Bollworm Helicoverpa armigera Hübner (Lepidoptera: Noctuidae)

Abstract:

African bollwormis a worldwide-spread species that shows a high degree of polyphagia and it is considered as one of the main agricultural pests in the world. Laboratory experiments were conducted in the Research Laboratory, College of Agricultural Studies, Sudan University of Science and Technology to evaluate the lethal effect of C. rotundusand D. stramonium on the H. armigeraand to investigate the synergistic effect of sesame oil and tested extracts by dipping methods. Five concentrations (4%, 6%, 8%, 10% and 12%) were used for each plant extract in a Completely Randomized Design. Tubers ethanolic extract of C. rotundus at 12% concentration caused 90% mortality after 72 hrs of application, whereas 12% concentration of seeds ethanolic extract of D. stramonium generate only 70% mortality after 72 hrs of exposure.

W...

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Ecological Significance of Residues Retention for Sustainability of Agriculture in the Semi-arid Tropics

Abstract:

In South Asia, land degradation is primarily a monsoon mediated phenomenon restricted to 2-3 rainy months. The overall strategy for land degradation neutrality should (i) favour actions that keep soils covered with residues and (ii) plant kharif (rainy season) crop before the onset of monsoons to provide soil cover. Retention of anchored residues provides surface cover, increases microbial activity, carbon sequestration, and availability of nutrients. Surface retained residues reduce root zone salinization, detoxify phytotoxic monomeric Al in acidic soils and enhance the potential for use of brackish ground water in crop production. Residues covers save irrigation water and overcome the ill effects of poor agronomic and water management practices. Early direct dry seeding in surface retained residues has the potential of making kharif season planting independent of the onset of monsoon rains in South Asia and helps reduce acreages of Kharif and Rabi fallow lands...

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Nature Inspired Bargain Optimization Algorithm for Effective Interpretation of Geoelectrical Data

Abstract:

Geoelectrical resistivity data collected from the ground contain lot of noises and errors. It requires efficient algorithm to reduce the errors to make an actual inversion models. Though different algorithm can be applied, nature inspired algorithm is more potential in inverting geoelectrical data in an elegant and comprehensive way. Bargain Optimization (BO) algorithm is framed on the concept of bargaining things to purchase for needs. In general, effective bargaining results in more profit and leads to loss when it fails. In this research work, Bargain Optimization algorithm is applied to invert geoelectrical data and the effective bargaining will take time to process and to obtain the required model. The input data is AB/2, apparent resistivity data and the inverted model through BO algorithm is successfully matched with the available litholog section of the study area. The output graphs have profit/loss bar graph, which reveals the status of bargaining durin...

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Efficacy of Ricinus communis L., Cassia occidentalis L. and Bacillus thuringiensis against Helicoverpa armigera Hübner (Lepidoptera: Noctuidae)

Abstract:

Helicoverpaarmigera is one of the most destructive pests of field crops worldwide. The Study was designed to investigate through laboratory screening the insecticidal activity of Ricinus communis, Cassia occidentalis and Bacillus thuringiensis var. Kurstaki (Btk) and their combinations against 2nd larval instar of H. armigera. Five concentrations (4%, 6%, 8%, 10% and 12%) of each plant extract and (0.62, 1.25, 2.5, 5, and 10 mg/ml) of Bt were used in this experiment. Mortality (%) was recorded after 24,48,72 and 96 hrs post treatment. The results showed that R. communis, C. occidentalis and Btkhave insecticidal activity against 2nd instar larvae of H. armigera Read Article

Prevalence and Risk Factors of HIV Infection among Children Born from HIV Positive Women Musanze District, Rwanda

Abstract:

In Rwanda the prevalence of mother-to-child HIV transmission is 1.5%, the prevalence was found to be higher in rural area. The purpose of this study was to determine the Prevalence and Risk Factors of HIV Infection among Children born from HIV Positive Women in Musanze District. The study findings help to decrease the rate of HIV infection among children born from mother HIV positive to zero. This study was conducted in Musanze District, Northern Province in Rwanda. The study targeted 420 HIV positive mothers who delivery in different health facilities located in Musanze district form January 2019 to December 2020 and their children. SPSS version 22 was used for analysis. Of 420 children born from HIV positive mothers 91.7% were aged between 18-24 months, 55.2% were female. The majority of HIV positive mothers 80.2% who participated in the study were married. The prevalence of HIV infection among children born from HIV positive women was 2.9%. Children whose moth...

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Use of the Remaining Sample from the Panbio COVID-19 Antigen Rapid Test Device for the Molecular Screening of the SARS-CoV-2 Variant of Concern B.1.1.7

Abstract:

Objective

Real-time surveillance of SARS-CoV-2 variants of concern (VOC) is of essential public health importance. Rapid Antigen Detection Tests (RAgDT) have become first-line COVID-19 diagnostic methods in many regions, but this strategy can hamper the surveillance of the virus variants due to their decentralized performance. The aim of this study was to assess the usefulness of the remaining sample of a widely used RAgDT (Panbio) for the surveillance of the B.1.1.7 VOC using molecular methods.

Methods

Symptomatic individuals and asymptomatic close contacts of confirmed cases were routinely screened for SARS-CoV-2 infection using the RAgDT in Primary Health Care Centers. After performing the test, the extraction tubes containing the remaining biological material of RAgDT-positive cases were sent to the clinical mic...

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