Recently Published Articles
Inguinal Hernia: A Probable Complication of Urinary Schistosomiasis in School Age Male Children in an Area Highly Endemic for Schistosoma Haematobium in Zambia.
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MicroRNA: New Era for Therapeutic Strategy in Ischaemic Heart Disease
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Over the last few decades, many research works highlighted the role of miRNAs on cardiac diseases. Ischaemic heart disease (IHD) or coronary heart disease is a condition that is mainly caused by atherosclerosis. It has been established that microribonucleic acids regulate many factors that are involved in the development and pathophysiology of IHD. As a result, there are great potential opportunities for miRNAs to be used as a biomarker for disease differentiation, as well as novel drug targets or therapeutics for the treatment and also as a diagnostic approach. As it is now evident that miRNAs play critical roles in the disease mechanisms, this review article tried to focus on the pathway, in which; the miRNAs stimulate the IHD to develop. By understanding the mechanisms, it will be possible to present a complete strategy of IHD treatment and also solving all the impediments that are highlighted in this article. Still, there are a number of limitations and obst...
Government Sponsored Health Insurance Coverage and Out-of-Pocket Spending Among Elderly in Kerala: A Cross-Sectional Study
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We aimed to find the population coverage, health service utilization and out-of-pocket spending among the elderly who are insured under Comprehensive Health Insurance Scheme (CHIS), Kerala through a longitudinal study of 600 non-rich households for nine months. The study found that only 57.7% the elderly were insured under CHIS which is lower than the population average of 80%. Single elderly from a socially backward caste, living alone in
Embryogenesis and Applications of Fingerprints- a review
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Fingerprint is an impression made by the friction ridges that are almost parallel at constant crest to crest wavelength. The pattern is dominated by central features, such as whorls, loops, arches and triradii. Fingerprints have been used for several decades in forensic and medical sciences. The fingerprints characteristics such uniqueness, consistency and universality are the main features that are used by forensic experts in identification processes, are well developed during intra-uterine life. Understanding embryogenesis of fingerprints is essential in linking its features to some disease conditions. The purpose of this review was to highlight information regarding establishment, formation, hypotheses and factors affecting fingerprints. Applications of the fingerprints in forensic and medical sciences were also highlighted. Both environmental (in utero) and genetic factors have role to play in the formation of the fingerprints. The primary role of fingerprints...
The Role of Helmet Use on Severity and Pattern of Maxillofacial Injuries Among Motorcycle Crash Victims Attending Mulago Hospital, Uganda
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The objective of the study was to establish the role of helmet use on severity and pattern of maxillofacial injuries among motorcycle crash victims attending Mulago Hospital. This was descriptive cross sectional case series study using a questionnaire in form of an oral interview, clinical examination and review of medical records of the patients. The pattern of injuries was assessed based on the demarcated regions of the face. The severities of the injuries were scored using the Facial Injury Severity Scale. The data were analysed using SPSS version 17.0. There were 105 participants (male/female: 97/8) aged 15 to 63 years. Most participants (n= 74, 70.5%) were riders and the rest were passengers. There were no female riders. Most participants were from Kampala and surrounding districts. Overall, 35.2% of the participants had helmets: 50% of the riders and 0% of the passengers. About 73% o the participants used Three Quarter Shell helmet design. There was no sig...
Nurses Working with Unlicensed Assistive Personnel: A Phenomenological Study
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To describe the attitudes and behavior of registered nurses in their professional interaction toward unlicensed assistive personnel (UAPs) and to identify areas to develop policy for an effective nursing development and workforce planning. One of the challenges health care systems have been addressing is the integration of the UAPs into the nursing care delivery systems.
Facilitators and Barriers to Health Care Access among the Elderly in Tanzania: A Health System Perspective from Managers and Service Providers.
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Tanzania is among the developing countries experiencing rapid growth of an ageing population, which has an implication in healthcare expenditure especially in resource poor settings where majority of elderly people cannot afford to pay for the cost of accessing health services. The country has developed the Tanzania National Health Policy (2007) and National Ageing Policy (2003), which, among other things, recognize the importance of having a healthcare system that provides free basic services to the vulnerable elderly population. This study aimed at exploring health service providers’ and managers’ perspectives on the factors facilitating or prohibiting access to health services among elderly people in Tanzania. The study adopted a qualitative approach and data were collected using semi-structured interviews. A total of 24 in-depth interviews were conducted with district healthcare managers, heads of public healthcare facilitie...
Colorectal Carcinogenic Pathways and Chemotherapeutic Responsiveness : A Review
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This review synthesizes key molecular pathways in colorectal carcinogenesis and relates them to differential chemotherapeutic responsiveness. It discusses mismatch repair, chromosomal instability, and serrated pathways, linking biomarkers to therapeutic decision‑making.
Short-Term and Chronic Effects of Aerobic and Resistance Exercise on Sleep in Young Men
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Despite the generally accepted benefits of exercise on sleep there remains limited research on potential differential effects by exercise type. The purpose of the present study was to examine short-term and chronic effects of aerobic and resistance exercise on various sleep quality parameters, as well as sleep duration. Generally healthy, previously sedentary young (27±3 years) men completed a 16-week aerobic and 16-week resistance exercise program in random order separated by a minimum of 6 weeks with no formal exercise. Each exercise program consisted of three supervised exercise sessions per week. Quality and duration of sleep was determined with a multi-sensor device that was worn prior to, during week 1 and week 16 of each exercise program. A total of 8 participants provided valid data on time spent awake after sleep onset, sleep latency, total sleep time, sleep efficiency and time spent in bed for both exercise programs. During week 1, aerobic exercise was ...
Changes in Statistics of Malignant Neoplasms of Central Nervous System Excluding Brain (ICD-10: C70, C72) In the Lower Silesia Region of Poland in the Years 2006-2012
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Epidemiological data concerning malignant neoplasms of meninges and central nervous system parts other than brain in Poland are reported to many medical databases run by various institutions and are incongruent with each other which makes their practical interpretation highly difficult. Data on registered cases of malignant neoplasms of meninges (C70-C70.9 ICD-10) and of spinal cord, cranial nerves and parts of central nervous system other than brain (C72-C72.9 ICD-10) in the years 2006-2012, made available by public healthcare insurance provider Narodowy Fundusz Zdrowia in Lower Silesia region of Poland (NFZ) and data on new cases from Polish national neoplasms registry Krajowy Rejestr Nowotworow (KRN), were analyzed. The study revealed that those neoplasms are rare in Lower Silesia region of Poland population, number of new cases dropped in the analyzed period, but the NFZ/KRN cases ratio increased significantly especially in case of malignant neoplasms of ce...