Recently Published Articles
Why Physiologically Cold weather can Increase Obesity Rates ?
Abstract:
Obesity generally accounts for a pathophysiology condition at which excessive body fats get accumulated in body parts. Among different - causes, ambient temperature such as cold environment can dramatically develop obesity in different individual. Cold weather influences the hormones that are related to the hunger and increases appetite toward overeating and subsequently inactivity . Controlling the calorie intakes through informative care are good strategies to prevent or govern obesity at any situation such as cold temperature
Comparison of an HPLC-MS/MS Method with Multiple Commercial ELISA Kits on the Determination of Levels of 8-oxo-7,8-Dihydro-2'-Deoxyguanosine in Human Urine
Abstract:
Analysis of 8-oxodG is usually conducted by either chromatography-based methods or by immunochemical methods commonly used based upon their low cost and high-throughput. However, concern regarding the accuracy of ELISA methods has complicated their use. We directly compare the levels of urinary 8-oxodG obtained by HPLC-MS/MS with three commercially available ELISA kits in this report. In the current study, a total of 9 human urine samples were analyzed by LC-MS/MS and three commonly used commercial available ELISA kits. We found that urinary 8-oxodG levels analyzed by HPLC-MS/MS [1.4 ± 0.3 nmol/mmol creatinine) were 7.6- to 23.5-fold lower than those ...
Effect of Coinfection by Fasciola hepatica and Mycobacterium bovis on Bovine Tuberculosis Immunodiagnosis in an Enzootic Area Hidalgo State, Mexico.
Abstract:
Parasitic infection by the
Dose Physiologically Performing Vigorous Exercises Good for Body Over Time
Abstract:
A commentary addresses the benefits and risks of vigorous exercise over time from a physiological perspective, discussing adaptation, monitoring, and individualized recommendations.
Why People With Liver (or hepatic ) Cancer Should Die in Short - Time?
Abstract:
This opinion challenges fatalistic framing of hepatic cancer prognosis. It advocates for nuanced discussion of staging, treatment advances, and supportive care, with clear communication to patients and families.
Should All Living Kidney Donors Receive Donor Health Insurance? - Ethical Guidance for Evaluating Policies and Actions that Provide Financial Benefits to Living Organ Donors
Abstract:
This review article provides ethical guidance for determining which kinds of financial benefits provided to living organ donors are ethically appropriate. It does so by way of ethical analysis of a policy case study: the National Kidney Registry (NKR) has implemented a donor insurance program to all its living donors. Is such a policy ethically supportable, or is it an unethical practice? The article proceeds as follows. First, a framework for grounding the ethical commitments of transplant programs is defended. It is argued that this framework can be accepted by all who work in transplant medicine, regardless of differences in ethical theory preference or background. Second, from this framework two ethical principles are formulated. (1) Living donors should, as far as possible, not be worse off for donating. (2) Disincentives towards donation should be removed as much as possible. Third, issues with unethical incentives are explored: undue inducement, commodific...
Analysis of Clinical Prognostic Variables for Triple Negative Breast Cancer Histological Grading and Lymph Node Metastasis
Abstract:
Triple Negative Breast Cancer (TNBC) is a type of breast cancer with very bad prognosis. Predicting the histological grade (HG) and the lymph nodes metastasis is crucial for developing more suitable treatment strategies. We present the main clinical and pathological variables to predict the histological grade and lymph nodes metastasis via novel machine learning techniques. These variables are currently being used for prognosis and treatment in medical practice. This analysis was performed using a database of 102 Caucasian women diagnosed with TNBC. The results were cross-validated using random simulations of this dataset. HG was predicted with an accuracy of 93.8% using a list of 6 prognostic var...
Dose Body Mass Index (BMI) Fit to Muscular Individual?
Abstract:
Body mass index (BMI) seemingly is an important scale for the body types determination in individual with different ethnicity. Accordingly, individual with BMI< 18.5 are classified as slim or underweight and people with BMI between 18.5 -24.9 are called normal body types. Subsequently, those individual with BMI between 25-29.9 are categorized as overweight and people with BMI > 30 are classified as obese people.
If we are not indexed, we do not exist?
Abstract:
An opinion editorial comments on indexing and visibility in scholarly communication. It encourages quality, openness, and ethical practices as pathways to discoverability and impact, with concrete steps for journals and authors.
Knowledge about Sexual and Reproductive Health among School Enrolled Adolescents in Tololar, Nicaragua, A Cross-Sectional Study
Abstract:
Nicaragua has the highest prevalence of teenage pregnancies in Latin America. Knowledge regarding sexual and reproductive health plays an integral part in sexual behavior. The objective was to assess school going adolescents' knowledge about sexual and reproductive health and possible factors affecting it in the semi-rural community of Tololar, Nicaragua. A cross-sectional study with a self-administered questionnaire on tablets was used for data collection. All 253 registered students at the school present at the time of fieldwork who gave written informed consent were deemed eligible for the study. A total of 225 participants in the ages of 11-19 years were included. Simple linear regression and multiple linear regression were performed analyzing the outcome knowledge. A p-value <0.05 was con...