All Articles

COVID-19: What we know

Abstract:

A concise overview synthesizes early knowledge on COVID‑19 in pediatrics, covering transmission, clinical spectrum, diagnostics, and prevention, and pointing to priorities for longitudinal study.

Nutritional Status of Reproductive Ethnic Woman Living in Chittagong Hill Tracts of Bangladesh: Influence of Socio-economic and Nutritional Factors

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This cross-sectional study assessed the nutritional status of ethnic reproductive women aged between 15-40 years, comprising 85 lactating women (LW) and 86 non-pregnant-non-lactating women (NPNLW) who lived in various parts of three hilly districts (Bandarban, Khagrachari and Rangamati) of the Chittagong Hill Tracts (CHTs) of Bangladesh.

Biodegradation of Methyl Parathion Using Pseudomonas stutzeri (MTCC 2643)

Abstract:

Pesticides applied in agricultural fields for crop protection result in the contamination of the environment. They also affect the flora and fauna as well as the quality of air, water and soil. Hence their remediation is of concern. Among different strategies available, microbial remediation is cost effective and ecofriendly. The present work is designed to test the efficiency of Pseudomonas stutzeri, a bacterial strain obtained from MTCC, IMTECH, Chandigarh, India. After treating with 50, 100, 150 and 200 ppm of methyl parathion, parameters like, orthophosphate released, pH and turbidity changes were monitored upto thirty hours. Degradation of 200 ppm concentration was confirmed by UV-Visible spectrophotometry and HPLC analysis. This strain effectively degraded methyl parathion and it can be used in the remediation of contaminated agricultural fields.

The Mechanism of Decline of Senescent Skeletal Muscle Satellite Cell Self-Renewal and Regenerative Proliferation: The Role of Heparan Sulfate-FGF-2--FGFR1-p38αMAPK Axis, Sprouty1, miR-1, miR-133 and miR-29a

Abstract:

Aging mammalian skeletal muscle satellite cells (MuSCs) undergo a decline of stem cell/progenitor cell proliferative and regenerative capacity, and the development of a physiological milieu characteristic of a state of chronic sterile inflammation. p38αMAPK and ERK1/2 are two major signaling pathways that regulate the age-associated decline of MuSC proliferative capacity. In this review we propose the following mechanism that links the p38αMAPK pathway to the decline of self-renewal and regenerative capacity of aged MuSCs: a) the HS-FGF-2-FGFR1-p38αMAPK-Axis, a tightly linked homeostatic signaling complex, is in synchrony with the autoinhibition of FGFR1; b) autoinhibition contributes to the Axis’ regulation of the homeostasis of P-p38αMAPK activity in juvenile MuSC; c) this combination of protein-protein interactions is characteristic of a juvenile cytoplasmic milieu of beneficial P-p38αMAPK ...

RETRACTED: Assessment of the Risk of Hemochromatosis in Polytransfused Sickle Cell Patients at the Abidjan Transfusion Therapy Unit

Abstract:

This article has been retracted on 29 January 2021. VIEW THE RETRACTION NOTICE (https://doi.org/10.14302/issn.2372-6601.jhor-25-5854)

In Côte d'Ivoire, sickle cell disease affects 14% of the population. It is responsible for significant morbidity and mortality. Transfusion is a significant element in the management of major sickle cell anemia, which exposes them to post-transfusion hemochromatosis. The biological diagnosis is based on the determination of serum iron and the transferrin saturation coefficient (CST). As the determination of the CST was not available in our exercise context in Côte d'Ivoire, we determined only the ferritinemia. The interest of this work lies in the therapeutic implication linked to the identification of patients at risk of hemochromatosis because chelators are difficult to access for most patients. This was a pr...

A Study on Redox Potential of Phytochemicals and their Impact on DNA

Abstract:

The phytochemicals are endowed with antioxidant activities because of the presence of plentiful polyphenols and many other phytochemicals. However, some recent reports have suggested that phytochemicals from certain plant species exhibit DNA damaging properties mainly due to presence of alkaloids. In the present study, pBR322, Salmonella typhi DNA, insect DNA and human DNA were treated with hexanolic extract of Argemone mexicana and Thevesia peruviana leaves to assess their DNA damaging abilities. Another set of experiments was carried out using the methanolic extracts of Citrus lemon leaves to assess their DNA protecting abilities from damage of DNA by extracts of A. mexicana and T. peruviana at 150000 ppm for all DNAs used. The results indicated that the leaves extract of A. mexicana Read Article

Retraction Note: Assessment of the Risk of Hemochromatosis in Polytransfused Sickle Cell Patients at the Abidjan Transfusion Therapy Unit

Abstract:

Study of the Nanocomposite Mo2C(1-x)-TiC(x)-SWCNTs by Field Actived Sparck Plasma Sintering Process

Abstract:

Nanocomposites are worn resistant materials used in cutting tool applications. The materials are composed of ultrafine powder hard phase grains surrounded by a tough binder phase carbon nanotubes (Mo₂C)_1-x–(TiC)_x (2≤x≤4)//1Wt% SWCNTs. Composite bicarbide Mo₂C-TiC was rapidly synthesised and simultaneously consolidated by field activated sintering technique (spark plasma sintering) at which the extensive volume expansion occurred as a function of the volumic fraction from 20 to 40 vol.% of TiC powders and 1 Wt.% of SWCNTs was reinforcement of the NCMC’s. The sintered powder mixture was examined by XRD patterns, the morphology of the obtained phase was observed by SEM and the phase compositions in different regions were analyzed by EDX. The composites were processed using Field Activated Sintering Technique, spark plasma sintering (SPS) at temperatures in the range of 1700-1800°C wit...

Incidence of Gastrointestinal Parasites in Zebu and N’dama Breeds from Cattle Ranches in Jos Plateau, Nigeria

Abstract:

The incidence of gastrointestinal parasites in Zebu and N’dama breeds known to be trypanotolerant cattle from some ranches in Jos Plateau was investigated at the peak of the raining season, August to October, 2018. A total of 150 cattle from some Ranches in Jos Plateau were randomly selected for faecal sampling out of which 85 were Zebu (Bos indicus) and 65 were N’dama (Bos taurus) breeds respectively. The samples were analyzed for ova of gastrointestinal parasites using the simple flotation and sedimentation techniques and the results were interesting. The strongyloids, Oesophagostomumradiatum had the highest incidence of 4.7% followed by the Trichostrongylus species with 4%. Fasciolagigantica and Haemonchusplacei both were 3.3%. Then Read Article

Structural Equation Modeling to Detect Predictors of CD4 Cell Count Change due to Long Term Antiretroviral Therapy Administered to HIV-Positive Adults at Felege Hiwot Teaching and Specialized Hospital, Bahir Dar, Ethiopia

Abstract:

The relationship between predictors and the variable of interest was estimated using a structural equation model which is used to predict latent variables. The main advantage of the SEM is the ability to estimate the direct and indirect pathways of the effect of the primary independent variable on the outcome, given sufficient sample sizes. Despite not directly modeling the mediated pathways, GLMMs excluding mediating variables performed well with respect to power, bias and coverage probability in modeling the total effect of the primary independent variables on the outcome. In longitudinal studies, data are collected from subjects at several time points. The main purpose of longitudinal analysis is to detecting the trends or trajectories of the variables of interest.