Research Topic · Peer-Reviewed

Primary Sclerosing Cholangitis

Primary Sclerosing Cholangitis (PSC) is a long-term disorder that affects the bile ducts in the liver. It is characterized by inflammation and scarring of the bile ducts which leads to gradual blockage of the flow of bile from the liver to the small intestine. This can lead to a variety of symptoms, including jaundi…

Curated from this journal's research 📚 3 peer-reviewed articles cited Cited 13× across the literature 🔖 ISSN 2578-2371 🗓 Reviewed June 2026

Overview

Primary Sclerosing Cholangitis (PSC) is a long-term disorder that affects the bile ducts in the liver. It is characterized by inflammation and scarring of the bile ducts which leads to gradual blockage of the flow of bile from the liver to the small intestine. This can lead to a variety of symptoms, including jaundice, fatigue, abdominal pain, and itching. In some cases, serious complications can occur if left untreated, such as liver failure, cirrhosis, or even primary biliary cholangitis. Treatment of PSC usually involves managing the symptoms and slowing down the progression of the disease. Medications, such as Ursodeoxycholic acid (UDCA) or corticosteroids, are used to reduce inflammation and reduce the size of the scarring. Surgery may also be recommended if the obstruction is severe. Primary Sclerosing Cholangitis is a serious condition that can affect quality of life, but proper diagnosis and treatment can help to manage symptoms and improve prognosis.

Research published in this journal

3 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 3 articles above have been cited 13 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Primary Sclerosing Cholangitis, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Spleen And Liver Research (ISSN 2578-2371).

Journal editorial board
Florin Graur · Romania

This page summarises published research for orientation; it is not medical or professional advice.