Research Topic · Peer-Reviewed

Liver Disease

Liver disease is any pathological process that impairs the structure or function of the liver, ranging from reversible injury to end-stage organ failure. Major categories include viral hepatitis, alcohol-related and metabolic (steatotic) liver disease, drug- and toxin-induced injury, autoimmune and cholestatic disor…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 46× across the literature 🔖 ISSN 2578-2371

Overview

Liver disease is any pathological process that impairs the structure or function of the liver, ranging from reversible injury to end-stage organ failure. Major categories include viral hepatitis, alcohol-related and metabolic (steatotic) liver disease, drug- and toxin-induced injury, autoimmune and cholestatic disorders, and hepatic malignancy. Because the liver controls protein and clotting-factor synthesis, bile secretion, glucose and lipid metabolism, and the clearance of toxins, disease manifests through jaundice, ascites, encephalopathy and coagulopathy and is detected biochemically through aminotransferases and synthetic-function markers. Chronic injury drives a fibrogenic sequence that can culminate in cirrhosis, portal hypertension and hepatocellular carcinoma. Work in this area covers the burden and trends of chronic liver disease in hospital-based cohorts, vitamin D deficiency in chronic liver disease and its clinical significance, genetic polymorphisms associated with fatty liver disease and treatment-related steatosis in HIV, tenofovir treatment of chronic hepatitis B, elastography in portal hypertension, polycystic liver disease, and alcohol-related associations among plasma TREM2, liver enzymes and an MS4A6A polymorphism. Epigenetic and nutritional influences on hepatic health are also represented. The journal publishes peer-reviewed clinical, genetic and experimental research across the breadth of hepatic disease, injury and protection.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 46 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Nov 2026.

A sample of recent works citing this journal's research on Liver Disease, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Journal of Spleen and Liver Research (ISSN 2578-2371).

Journal editorial board
Junfei Jin · China Ali Coskun · Turkey Florin Graur · Romania

This page summarises published research for orientation; it is not medical or professional advice.