Overview
Cholelithiasis is the medical term for the formation of gallstones, solid concretions that develop in the gallbladder from components of bile, most commonly cholesterol or pigment (bilirubin) stones. It is a common condition, and while many stones remain silent and asymptomatic, they can obstruct the cystic or common bile duct and cause biliary colic, cholecystitis, jaundice, pancreatitis, and other complications. Risk factors include female sex, increasing age, obesity, rapid weight loss, pregnancy, and certain metabolic and dietary patterns. Diagnosis relies chiefly on imaging such as ultrasonography, and symptomatic disease is frequently treated by surgical removal of the gallbladder (cholecystectomy). Research in Spleen and Liver Research engages directly with this condition, including a retrospective study evaluating gallbladder mucosal changes in relation to stone type in patients undergoing laparoscopic cholecystectomy, while related work in the publisher's portfolio has examined microbial biofilm formation on simulated gallstones, relevant to the link between gallstones and chronic Salmonella carriage. This page gathers peer-reviewed, open-access research relevant to cholelithiasis, gallstone disease, and its diagnosis and surgical management.
Research published in this journal
3 peer-reviewed articles, ranked by relevance. Each links to its DOI.
How this research is being cited
The 3 articles above have been cited 13 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Infection
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2025 · PLOS One
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2025 · Frontiers in Microbiology
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2025 · Open Forum Infectious Diseases
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2025 · Frontiers in Microbiology
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2025 · Open Forum Infectious Diseases
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2025 · PLoS ONE
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Aliyah N. Bennett et al. · 2025 · Frontiers in Cellular and Infection Microbiology
A sample of recent works citing this journal's research on Cholelithiasis, linking to each citing work.