Research Topic · Peer-Reviewed

Acute Phase Proteins

Acute phase proteins are a group of blood proteins whose concentrations change significantly in response to inflammation, infection, tissue injury, or other physiological stresses. These proteins, produced primarily by the liver, serve as biomarkers of systemic inflammation and immune response. Research published in…

Curated from this journal's research 📚 4 peer-reviewed articles cited Cited 6× across the literature 🔖 ISSN 2578-2371 🗓 Reviewed July 2026

Overview

Acute phase proteins are a group of blood proteins whose concentrations change significantly in response to inflammation, infection, tissue injury, or other physiological stresses. These proteins, produced primarily by the liver, serve as biomarkers of systemic inflammation and immune response. Research published in Spleen And Liver Research has examined acute phase proteins across diverse clinical contexts, including their role as therapy response indicators in canine leishmaniasis, where total proteins and globulin fractions help assess treatment efficacy in infected dogs. The journal has also explored inflammatory markers in gestational diabetes, investigating proinflammatory cytokines that trigger acute phase responses during pregnancy complications. Additional studies have addressed protein metabolism in cancer cachexia, examining how nutritional interventions with immunonutrients affect protein status in patients experiencing inflammation-driven wasting. Further research has investigated genetic polymorphisms affecting coagulation-related acute phase proteins in cardiovascular disease risk. Understanding acute phase protein dynamics is clinically important because these molecules provide accessible, measurable indicators of disease activity, treatment response, and metabolic stress across multiple organ systems, particularly those involving hepatic and splenic function in inflammatory and infectious conditions.

Research published in this journal

4 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 4 articles above have been cited 6 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Acute Phase Proteins, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Spleen And Liver Research (ISSN 2578-2371).

Journal editorial board
Florin Graur · Romania

This page summarises published research for orientation; it is not medical or professional advice.