Hyperbilirubinemia

Hyperbilirubinemia is a condition in which an excess amount of bilirubin builds up in the body. Bilirubin is a yellow-orange pigment that is a breakdown product of red blood cells. High levels of hyperbilirubinemia can lead to a jaundiced yellowish discoloration of the skin and whites of the eyes. Hyperbilirubinemia may occur due to a variety of reasons, including liver damage, inherited genetic disorders, or inadequate production of enzymes or proteins that are necessary for bilirubin metabolism. Hyperbilirubinemia is typically diagnosed by examining a patient's levels of total and direct bilirubin in the blood. Treatment for hyperbilirubinemia is focused on managing the underlying cause, and may include medications such as antibiotics, antivirals, or phototherapy. Hyperbilirubinemia is a dangerous condition that can lead to complications such as brain damage, so prompt diagnosis and treatment is essential.