Research Topic · Peer-Reviewed

Systemic Inflammatory Response Syndrome

Systemic Inflammatory Response Syndrome (SIRS) is a widespread inflammatory condition characterized by the body's exaggerated immune response to various insults, including infection, trauma, or toxins, manifesting through clinical signs such as altered temperature, heart rate, respiratory rate, and white blood cell …

Curated from this journal's research 📚 6 peer-reviewed articles cited Cited 8× across the literature 🔖 ISSN 2832-4048 🗓 Reviewed June 2026

Overview

Systemic Inflammatory Response Syndrome (SIRS) is a widespread inflammatory condition characterized by the body's exaggerated immune response to various insults, including infection, trauma, or toxins, manifesting through clinical signs such as altered temperature, heart rate, respiratory rate, and white blood cell count. Research published in this journal has examined SIRS across multiple contexts, including experimental models using cecal slurry, lipopolysaccharide, and bacterial challenges in rodents to evaluate inflammatory cytokine responses and the antioxidant and anti-inflammatory effects of proprietary formulations in brain tissues. Additional studies have explored SIRS-related complications in clinical settings, such as assessing vitamin D levels in organophosphorus poisoning patients, evaluating adverse drug reactions in HIV-positive patients receiving antiretroviral therapy, and analyzing risk factors for gastric dilatation-volvulus in veterinary medicine. One investigation examined a myotoxic enzyme from snake venom, relevant to understanding tissue damage and inflammatory cascades. This body of work reflects the syndrome's significance across human and veterinary medicine, where early recognition and understanding of inflammatory mechanisms remain critical for managing diverse pathological conditions that can progress to organ dysfunction and sepsis if untreated.

Research published in this journal

6 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 6 articles above have been cited 8 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Systemic Inflammatory Response Syndrome, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Skeletal Muscle (ISSN 2832-4048).

Journal editorial board
Gerhard Meissner · United States Min Du · United States Jeong-Rae Kim · South Korea

This page summarises published research for orientation; it is not medical or professional advice.