Gram-negative bacteria are a major class of bacteria defined by their failure to retain the crystal violet dye in Gram staining, a property that reflects a thin peptidoglycan cell wall surrounded by an outer membrane rich in lipopolysaccharide. This outer membrane serves as a protective barrier that limits the entry…
Gram-negative bacteria are a major class of bacteria defined by their failure to retain the crystal violet dye in Gram staining, a property that reflects a thin peptidoglycan cell wall surrounded by an outer membrane rich in lipopolysaccharide. This outer membrane serves as a protective barrier that limits the entry of many antibiotics and contributes to multidrug resistance, while its lipopolysaccharide component can provoke fever and inflammation in infected hosts. The group encompasses numerous environmental species and important human pathogens, including Escherichia coli, Klebsiella, Salmonella, and Pseudomonas, that are responsible for respiratory, urinary, gastrointestinal, and other infections. Research relevant to this topic in the journal addresses the identification, resistance, and biological effects of Gram-negative organisms, including carbapenem-resistance mechanisms in Klebsiella pneumoniae and in avian pathogenic Escherichia coli, the oral pathogen Porphyromonas gingivalis, and broader analyses of antimicrobial resistance. Additional studies examine lipopolysaccharide-induced oxidative stress and tissue damage, the antibacterial activity of natural and synthetic compounds, the bacteriological quality of water, and pathogenic bacteria recovered from animal and environmental sources. Across this work, attention centers on accurate detection, the growing problem of antibiotic resistance, the inflammatory potential of endotoxin, and the development of effective antibacterial interventions.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 126 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Gram Negative Bacteria, linking to each citing work.