Research Topic · Peer-Reviewed

Lung Cancers

Lung cancers are malignant neoplasms arising from the epithelium of the bronchi, bronchioles, or alveoli, and they rank among the most frequently diagnosed and lethal cancers worldwide. They are classified principally into non-small-cell lung cancer, which comprises adenocarcinoma, squamous cell carcinoma, and large…

Curated from this journal's research 📚 7 peer-reviewed articles cited Cited 8× across the literature 🔖 ISSN 2642-9241 🗓 Reviewed June 2026

Overview

Lung cancers are malignant neoplasms arising from the epithelium of the bronchi, bronchioles, or alveoli, and they rank among the most frequently diagnosed and lethal cancers worldwide. They are classified principally into non-small-cell lung cancer, which comprises adenocarcinoma, squamous cell carcinoma, and large-cell carcinoma, and small-cell lung cancer, a neuroendocrine subtype noted for rapid growth and early metastasis. Carcinogenesis is driven by the accumulation of somatic mutations in oncogenes and tumour-suppressor genes, often following prolonged exposure to tobacco smoke, radon, asbestos, or ambient air pollution, with recurrent alterations in genes such as KRAS, EGFR, and TP53 shaping tumour behaviour and treatment response. Clinical presentation may include persistent cough, haemoptysis, chest pain, dyspnoea, and weight loss, though early disease is frequently asymptomatic, underscoring the value of low-dose computed tomography screening in high-risk populations. Staging integrates tumour size, nodal involvement, and distant spread to guide management, which spans surgical resection, radiotherapy, platinum-based chemotherapy, molecularly targeted agents directed at actionable driver mutations, and immune checkpoint inhibitors. Molecular biomarkers increasingly inform diagnosis, prognosis, and the selection of personalised therapy across the disease spectrum.

Research published in this journal

7 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 7 articles above have been cited 8 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Lung Cancers, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Respiratory Diseases (ISSN 2642-9241).

Journal editorial board
Jason Akulian · United States

This page summarises published research for orientation; it is not medical or professional advice.