Journal of Psychophysiology Practice and Research

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Psychophysiology Practice and Research-Animal models of neuropsychiatric and neurologic disorders with an greater emphasis on schizophrenia-Jeffrey Eells

United States

Ph.D., Southern Illinois University, Postdoctoral Fellow, University of North Carolina at Chapel Hill; National Institute for Diabetes and Digestive and Kidney Diseases


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Jeffrey Eells


Brody School of Medicine 600 Moye Blvd Mail Stop 620 East Carolina University Greenville, NC 27834-4354

Research Interests:

Animal models of neuropsychiatric and neurologic disorders with an greater emphasis on schizophrenia, addiction, and Parkinson's disease



  1. Eells, J.B., J.A. Misler, and V.M. Nikodem. 2006. Reduced tyrosine hydroxylase and GTP cyclohydrolase mRNA expression, tyrosine hydroxylase activity, and associated neurochemical alterasions in Nurr1-null heterozygous mice. Brain Res. Bull. 70: 186-195. PMID: 16782508.
  2. Gil, M., C. McKinney, M.K. Lee, J.B. Eells, M.A. Phyillaier, and V.M. Nikodem. 2007. Regulation of GTP-cyclohydrolase 1 gene expression by orphan receptor Nurr1 in cell culture and in vivo. J. Neurochem. 101: 142-150. PMID: 17394463.
  3. Moore, T.M., T. Brown, M. Cade, and J.B. Eells. 2008. Alterations in amphetamine-stimulated dopamine overflow due to the Nurr1-null heterozygous genotype and postweaning isolation. Synpase. 62: 764-774. PMID: 18655117.
  4. Eells, J.B. and T.W. Brown. 2009. Repeated developmental exposure to chlorpyrifos and methyl parathion causes persistent alterations in nicotinic acetylcholine subunit mRNA expression with chlorpyrifos altering dopamine metabolite levels. Neurotoxiol. Teratol. 31: 90-103. PMID: 18977431.
  5. Scott, V.L., L.A. Shack, J.B. Eells, P.L. Ryan, J.R. Donaldson, and K.S. Coats. 2011. Immunomodulator expression in trophoblasts from the feline immunodeficiency virus (FIV)-infected cat. Virol. J. 8: 336. PMID: 21729293.
  6. Eells, J.B., J. Wilcots, S. Sisk, and S.X. Guo-Ross. 2011. NR4A gene expression is dynamically regulated in the ventral tegmental area dopamine neurons and is related to expression of dopamine neurotransmission genes. J. Mol. Neurosci. 46: 545-553. PMID: 21932041.
  7. Kummari, E., S.X. Guo-Ross, and J.B. Eells. 2015. Laser capture microdissection – a demonstration of the isolation of individual dopamine neurons and the entire ventral tegmental area. J. Vis. Exp. 96: e52336. PMID: 25742438.
  8. Eells, J.B., A. Varela-Stokes, S.X. Guo-Ross, E. Kummari, H.M. Smith, E. Cox, and D.S. Lindsay. 2015. Chronic toxoplasma gondii in Nurr1-null heterozygous mice exacerbates elevated open field activity. PLoS ONE. 10: e0119280. PMID: 25855987.
  9. Yang, E.J., J.V. Stokes, E. Kummari, J. Eells, and B.L. Kaplan. 2016. Immunomodulation by subchronic low dose 2,3,7,8-Tetrachlorodibenzo-p-dioxin in experimental autoimmune encephalomyelitis in the absence of pertussis toxin. Toxicol. Sci. 151: 35-43. PMID: 26822306.
  10. Carr, R.L., N.H. Armstrong, A.T. Buchanan, J.B. Eells, A.N. Mohammed, M.K. Ross, and C.A. Nail. 2017. Decreased anxiety in juvenile rats following exposure to low levels of chlorpyrifos during development. NeuroTox. 59: 183-190. PMID: 26642910.