Overview
Epigenetics is the study of heritable, reversible changes in gene expression that occur without alteration of the DNA sequence itself, mediated by modifications layered onto the genome and its associated proteins. The central mechanisms are DNA methylation, post-translational modification of histones, chromatin remodeling, and regulation by non-coding RNAs including microRNAs, which together control the accessibility of genes to the transcriptional machinery and thereby shape patterns of gene activity. These epigenetic marks orchestrate development and cellular differentiation, can be transmitted through cell division, and respond to environmental, nutritional, and lifestyle inputs, linking external factors to gene regulation and to diseases such as cancer. Within proteomics and genomics research, epigenetic regulation connects genome-level information to the proteins and phenotypes that emerge from it, and its analysis complements the study of gene and protein expression. Research relevant to this topic includes the interplay of epigenetics and nutrition, stem-cell-derived factors acting as epigenetic regulators to reverse tissue damage, epigenetic regulation of candidate genes in cardiovascular disease, the epigenetic relevance and mechanisms of endocrine-disrupting chemicals, epigenetic regulation of neurotrophin gene expression in chronic pain, microRNA-based nucleic-acid technologies for disease screening, and epigenetic pathways underlying genetic variation and crop breeding, reflecting the broad reach of epigenetic mechanisms across molecular biology.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Some Regulation Mechanisms of Candidate Genes for Human Cardiovascular Diseases
Endocrine Disrupting Chemicals: Epigenetic Relevance and Mechanisms
Research Status and Application Prospect of Epigenetic Regulation of BDNF Gene Expression in Chronic Pain
Use of Stem Cell Growth and Differentiation Factors (Scdsf) in Central Vertigo
The Use of Mirnas as Activators of Dental Implant Surfaces, A Review
Evolution of the Concept of Evolution
Conservation, Creation, and Evolution: Revising the Darwinian Project
Rice Epigenetic Pathways: Great Genetic Variation and Implication for Rapid Rice Breeding
How this research is being cited
The 12 articles above have been cited 33 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Nov 2026.
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2026 · Journal of Otolaryngology Advances
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2025 · Communications Biology
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2025 · Artificial Life
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2025 · Current Medicinal Chemistry
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2025 · Scientific Reports
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2025 · Communications Biology
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2025 · Ethical Review of Social Sciences
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2025 · Scientific Reports
A sample of recent works citing this journal's research on Epigenetics, linking to each citing work.