Research Topic · Peer-Reviewed

Clinical Proteomics

Clinical proteomics is the application of proteomic technologies to human health and disease, identifying and quantifying proteins in tissues and biofluids such as blood, plasma, saliva and urine to discover biomarkers and inform diagnosis, prognosis and treatment. It translates the analytical power of proteomics in…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 15× across the literature 🔖 ISSN 2326-0793 🗓 Reviewed July 2026

Overview

Clinical proteomics is the application of proteomic technologies to human health and disease, identifying and quantifying proteins in tissues and biofluids such as blood, plasma, saliva and urine to discover biomarkers and inform diagnosis, prognosis and treatment. It translates the analytical power of proteomics into the clinic, linking changes in protein abundance and modification to disease states and therapeutic response, and increasingly feeds personalised and precision-medicine strategies. Core methods include mass-spectrometry-based discovery and quantification, isotope-labelling and ion-current-based approaches, and the integration of proteomic findings with genomic and bioinformatic analysis to interpret pathways and validate candidate markers. Research relevant to this area includes integrated proteomic and genomic techniques applied to cancer diagnostics and personalised medicine; the proteomics and bioinformatics status of the Human Proteome Project in disease diagnosis and treatment; analysis of plasma TREM2 levels and genetic polymorphism in relation to liver enzymes in alcohol use disorder; methods for discovery and quantification in mass-spectrometry-based proteomics; quantitative proteomics using a 15N SILAC mouse; the proteomic response to targeted drug treatment; reviews of molecular biomarkers; and bioinformatics of metabolomics in type 2 diabetes. Foundational contributions on proteome coverage from single proteins to whole-body analysis underpin the field. Together this work advances biofluid and tissue biomarker discovery, mechanistic understanding of disease, and the clinical translation of protein measurements.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2013

Quantitative Proteomics Using 15N SILAC Mouse

I. Chen EmilyCorresponding author
Stony Brook University, Proteomics Center, School Of Medicine, NY
Proteomics and Genomics Research Cited by 4 doi:10.14302/issn.2326-0793.jpgr-13-252
2014

Bioinformatics of Metabolomics in Diabetes Mellitus Type 2

Ahmad Sliem HamdyCorresponding author
Biochemistry and internal Medicine*, Basic oral and medical sciences, College of dentistry, Qassim University, Saudi Arabia
Bioinformatics And Diabetes Cited by 2 doi:10.14302/issn.2374-9431.jbd-13-212
2018

Molecular Biomarkers: A Brief Review

Tarassishin LeonidCorresponding author
 Department of Biological Sciences.
Proteomics and Genomics Research doi:10.14302/issn.2326-0793.jpgr-18-2418

How this research is being cited

The 12 articles above have been cited 15 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Clinical Proteomics, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Proteomics and Genomics Research (ISSN 2326-0793).

Journal editorial board
Sutopa Dwivedi · United States Liuyang Wang · United States Juan Sainz · Spain

This page summarises published research for orientation; it is not medical or professional advice.