Research Topic · Peer-Reviewed

Cardiovascular Proteomics

Cardiovascular proteomics is the systematic study of the proteins expressed in the heart, blood vessels and circulating plasma, characterising their abundance, post-translational modifications and interactions to understand cardiovascular physiology and disease. By profiling the protein complement of cardiac and vas…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 71× across the literature 🔖 ISSN 2326-0793 🗓 Reviewed July 2026

Overview

Cardiovascular proteomics is the systematic study of the proteins expressed in the heart, blood vessels and circulating plasma, characterising their abundance, post-translational modifications and interactions to understand cardiovascular physiology and disease. By profiling the protein complement of cardiac and vascular tissue and of biofluids, it seeks biomarkers for diagnosis, risk stratification and treatment monitoring, and elucidates the molecular pathways underlying conditions such as atherosclerosis, hypertension, heart failure and ischaemic injury. Methodologically it relies on mass-spectrometry-based discovery and quantification, including ion-current-based and metabolic-labelling strategies, integrated with bioinformatic and genomic analysis to link proteins to genetic variants and pathways. Research relevant to this area includes bioinformatic analysis of coronary-disease-associated SNPs and genes to identify proteins implicated in atherosclerosis pathogenesis; methods for discovery and quantification in mass-spectrometry-based proteomics; quantitative proteomics using a 15N SILAC mouse; the proteomic response to targeted pharmacological treatment; assessment of the Human Proteome Project in disease diagnosis; reviews of molecular biomarkers; and integrated proteomic and genomic techniques for diagnostics and personalised medicine. Foundational work on proteome coverage from single proteins to whole-body analysis supports these efforts. The field connects proteomics, cardiology and bioinformatics to translate protein-level measurements into mechanistic insight and clinically actionable markers for cardiovascular disease.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2013

Quantitative Proteomics Using 15N SILAC Mouse

I. Chen EmilyCorresponding author
Stony Brook University, Proteomics Center, School Of Medicine, NY
Proteomics and Genomics Research Cited by 4 doi:10.14302/issn.2326-0793.jpgr-13-252

How this research is being cited

The 12 articles above have been cited 71 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Cardiovascular Proteomics, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Proteomics and Genomics Research (ISSN 2326-0793).

Journal editorial board
Sutopa Dwivedi · United States Liuyang Wang · United States Juan Sainz · Spain

This page summarises published research for orientation; it is not medical or professional advice.