Bacterial infections occur when pathogenic bacteria colonize and proliferate within host tissues, causing disease through invasion, toxin production, and the host inflammatory response. Outcomes depend on bacterial virulence factors, inoculum, route of entry, and host immune status, and range from localized infectio…
Bacterial infections occur when pathogenic bacteria colonize and proliferate within host tissues, causing disease through invasion, toxin production, and the host inflammatory response. Outcomes depend on bacterial virulence factors, inoculum, route of entry, and host immune status, and range from localized infections of the urinary, respiratory, gastrointestinal, and skin compartments to systemic sepsis. Pathogens are broadly distinguished by Gram-staining, morphology, and metabolic and resistance characteristics, with clinically important examples including Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli, and other Enterobacterales. A defining contemporary challenge is antimicrobial resistance, encompassing methicillin-resistant S. aureus and carbapenem-resistant Gram-negative organisms, which narrows therapeutic options and is driven in part by inappropriate antibiotic prescribing; antimicrobial stewardship and surveillance of susceptibility patterns are therefore central to control. Diagnosis combines culture, susceptibility testing, and molecular and spectrometric characterization, while management integrates targeted antimicrobial therapy, infection prevention, and attention to the host microbiota. The peer-reviewed research assembled here reflects these themes, including carbapenem-resistance and susceptibility patterns in Klebsiella pneumoniae, antibiotic-resistant urinary tract infection, in vitro activity of agents against resistant staphylococci, antibiotic prescribing practices for respiratory infection, single-domain antibodies against pathogenic E. coli, and the role of nutrition and the microbiota, alongside analyses of antimicrobial agents relevant to bacterial disease.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 32 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Bacterial Infections, linking to each citing work.