Age-related diseases are conditions whose incidence and severity rise with advancing age, arising from the cumulative biological changes of senescence that progressively impair tissue function and resilience. They include cardiovascular disease, many cancers, neurodegenerative disorders, metabolic dysfunction, muscu…
Age-related diseases are conditions whose incidence and severity rise with advancing age, arising from the cumulative biological changes of senescence that progressively impair tissue function and resilience. They include cardiovascular disease, many cancers, neurodegenerative disorders, metabolic dysfunction, musculoskeletal decline, and age-related sensory impairment, and are linked to underlying processes such as telomere attrition, oxidative damage, chronic inflammation, and altered cellular maintenance. Within preventive medicine, understanding and mitigating these processes is central to preserving healthy lifespan. Research bearing on age-related disease addresses both mechanisms of aging and strategies to delay or attenuate functional decline. Studies of telomerase activity, sirtuins, and longevity in experimental models examine the molecular determinants of biological aging, while work on oxidative telomere attrition and nutritional antioxidants explores how diet may influence these pathways. Functional and clinical research considers muscle dysfunction and sarcopenia, cognitive decline and the effects of cognitive and aerobic training, nutritional assessment in older adults, and the impact of sensory impairment such as low vision on quality of life. Allied topics include age-related macular degeneration, the management of overweight and obesity, and the ethical dimensions of regenerative approaches. Collectively this literature frames age-related disease as a multisystem challenge addressed through prevention, lifestyle, and the biology of aging.
11 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 11 articles above have been cited 81 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Age Related Diseases, linking to each citing work.