Research Topic · Peer-Reviewed

Polypeptide

A polypeptide is a continuous, unbranched chain of amino acids linked by peptide bonds, forming the primary structure of proteins. Research published in this journal addresses polypeptides across multiple biological contexts, from their role in genetic disorders to their function in cellular processes and disease me…

Curated from this journal's research 📚 7 peer-reviewed articles cited Cited 50× across the literature 🗓 Reviewed June 2026

Overview

A polypeptide is a continuous, unbranched chain of amino acids linked by peptide bonds, forming the primary structure of proteins. Research published in this journal addresses polypeptides across multiple biological contexts, from their role in genetic disorders to their function in cellular processes and disease mechanisms. Studies have examined polypeptide synthesis defects in metabolic conditions such as phenylketonuria, where mutations in the 6-pyruvoyltetrahydropterin synthase gene affect enzyme production. Other work has explored polypeptide-based biomarkers for distinguishing malignant tumors from benign tissue, particularly in gynecological cancers. Investigations into surfactant protein variants have revealed how different polypeptide isoforms influence the alveolar macrophage proteome, affecting immune responses in the lung. Additional research has applied advanced mass spectrometry techniques to identify and characterize polypeptide interactions in mammalian cells, improving methods for studying protein complexes. The journal has also published work on polypeptide hormones in endocrine tumor syndromes and bioactive polypeptides from plant sources with potential metabolic effects. Understanding polypeptide structure, function, and variation remains fundamental to elucidating disease mechanisms, developing diagnostic markers, and identifying therapeutic targets across diverse medical and biological disciplines.

Research published in this journal

7 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 7 articles above have been cited 50 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Polypeptide, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Peptides.

Journal editorial board
Laura Zaccaro · Italy Emilia Pedone · Italy Dulari Jayawardena · United States

This page summarises published research for orientation; it is not medical or professional advice.