Peptide Nucleic Acids

Peptide Nucleic Acids (PNAs) are a synthetic molecule made of peptide and nucleic acid components, combining the recognition ability of peptides with the genetic stability of DNA. PNAs are widely used in biotechnology for genetic manipulation, drug delivery and detection of genetic material. They can be used to stop the replication of foreign DNA, creating a target-specific inhibition. PNAs can also inhibit the expression of specific target genes. Additionally, by mimicking DNA, PNAs can bind to complementary sequences in living cells, allowing scientists to better understand gene regulation. These properties make PNAs highly valuable in both research and clinical applications, and they have been widely used in gene therapy studies, diagnostics and therapeutic drug delivery.

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Related Articles

15 article(s) found

Physicochemical and Fatty Acids Composition of Barberry Integerrima Seed

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Template Independent Synthesis of Nucleic Acid Libraries

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The Antidepressant-Like Activity of the New Tetrapeptide Neuroprotector Kk-1, Homologous of Acth15-18 Sequence (An Experimental Study)

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Implementing High Energy Liquid Nutrition, Omega-3 Fatty Acids and Nutritional Supplements for the Treatment of Anorexia Nervosa

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Research Progress of the Functional Nucleic Acid Techniques in GMO Detection

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Preoperative and Postoperative N-terminal Pro B-type Natriuretic Peptide Levels Predict Cardiac Morbidity and Mortality in Patients Undergoing Colorectal Cancer Resection

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In Silico Inhibition of Essential Candida albicans Proteins by Arenicin, a Marine Antifungal Peptide

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Amino Acids and their Derivatives in Pathogenesis and Treatment of Liver Diseases

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Use of Microfluidic Assays to Develop Reliable and Economic Nucleic Acid Application Technologies, Employing MicroRNAs for the Diagnostic Screening of Colon Cancer in Human Stool in Low-Resource Settings

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Use of Microfluidic Assays to Develop Reliable and Economic Nucleic Acid Application Technologies, Employing MicroRNAs for the Diagnostic Screening of Colon Cancer in Human Stool in Low-Resource Settings

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Iodometric Determination of Neutral Amino Acids Using Potassium Iodate

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Clinical Use of Peptide-Based Formula (Peptamen Junior®, Nestle) in the Paediatric Population

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Novel Methods for Inhibiting Amyloidogenesis in the Presence of Peptides to Block Hydrophobic Interactions

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Peptide Synthesis in Aqueous Solution With a Reusable Solid Phase

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Protection Side Chain of Lysine by Host-Affinity Molecules during Solid Phase Peptide Synthesis in Aqueous Phase

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