Research Topic · Peer-Reviewed

Ulcers

An ulcer is a discontinuity or break in the skin or in an epithelial or mucosal surface that extends through the surface layer into underlying tissue, resulting from the loss of cells following inflammation, ischaemia, infection or trauma. Ulcers are classified by site and mechanism and include peptic ulcers of the …

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 29× across the literature 🗓 Reviewed June 2026

Overview

An ulcer is a discontinuity or break in the skin or in an epithelial or mucosal surface that extends through the surface layer into underlying tissue, resulting from the loss of cells following inflammation, ischaemia, infection or trauma. Ulcers are classified by site and mechanism and include peptic ulcers of the stomach and duodenum, oral and aphthous ulcers, cutaneous ulcers, and chronic wounds such as diabetic foot and venous leg ulcers. Their pathogenesis involves an imbalance between mucosal or tissue-protective factors and injurious influences, with contributing causes including Helicobacter pylori and other infection, non-steroidal anti-inflammatory drugs, gastric acid, vascular insufficiency, neuropathy, pressure and impaired healing. Complications may include bleeding, secondary infection, perforation and delayed closure, and management combines treatment of the underlying cause, infection and inflammation control, wound care and lifestyle modification. Research grouped under this term reflects this breadth across ulcer types: oral ulceration, diabetic foot and leg ulceration with peri-wound neuropathy healing, cutaneous ulceration related to topical corticosteroid abuse and to hydroxyurea, and the market and quality dimensions of anti-ulcer drugs. The peer-reviewed literature in this area spans the aetiology, pathophysiology, healing and treatment of mucosal and cutaneous ulceration across gastrointestinal, oral, dermatological and chronic-wound contexts.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2023

Oral Ulceration

Exact topic International Journal of General Practice doi:10.14302/issn.2692-5257.ijgp-22-4071

How this research is being cited

The 12 articles above have been cited 29 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Ulcers, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Pancreas.

Journal editorial board
Giuseppe Maulucci · Italy Carlo Molino · Italy Cosimo Sperti · Italy

This page summarises published research for orientation; it is not medical or professional advice.