Research Topic · Peer-Reviewed

Pancreatic Cancer

Pancreatic cancer is a malignancy arising from the exocrine or endocrine tissue of the pancreas, most commonly ductal adenocarcinoma, characterised by aggressive local invasion, early metastasis and frequently late presentation. Tumours typically develop in the pancreatic head, body or tail and may present with pain…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 21× across the literature 🗓 Reviewed June 2026

Overview

Pancreatic cancer is a malignancy arising from the exocrine or endocrine tissue of the pancreas, most commonly ductal adenocarcinoma, characterised by aggressive local invasion, early metastasis and frequently late presentation. Tumours typically develop in the pancreatic head, body or tail and may present with painless obstructive jaundice, abdominal or back pain, weight loss, cachexia, or, in advanced disease, gastrointestinal bleeding. The disease is notable for resistance to therapy and poor prognosis, with diagnosis supported by cross-sectional imaging, tissue sampling and serum markers such as CA 19-9, carcinoembryonic antigen and bilirubin, and management spanning surgical resection where feasible, chemotherapy and radiotherapy, alongside supportive nutritional and palliative care. Research and tumour biology in this area address diagnosis, presentation, systemic effects and supportive management. Studies collected under this term include comparison of CEA and bilirubin against CA 19-9 at initial presentation in a non-tertiary setting, massive haematemesis as the initial presentation of advanced pancreatic adenocarcinoma, protein- and energy-dense immunonutrient supplementation for cancer cachexia, oxidative telomere attrition and biological aging, neutrophil-to-lymphocyte ratio in carcinoma, drug-design approaches, and complementary and alternative cancer therapies. The peer-reviewed literature in this area examines the clinical presentation, biomarkers, supportive nutrition and management of pancreatic malignancy and related oncological themes.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 21 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Pancreatic Cancer, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Pancreas.

Journal editorial board
Giuseppe Maulucci · Italy Carlo Molino · Italy Cosimo Sperti · Italy

This page summarises published research for orientation; it is not medical or professional advice.