Cancer is a group of diseases characterized by the uncontrolled proliferation and spread of abnormal cells that arise from the stepwise accumulation of genetic and epigenetic alterations affecting oncogenes, tumour-suppressor genes, and DNA-repair pathways. Malignant cells acquire hallmark capabilities including sus…
Cancer is a group of diseases characterized by the uncontrolled proliferation and spread of abnormal cells that arise from the stepwise accumulation of genetic and epigenetic alterations affecting oncogenes, tumour-suppressor genes, and DNA-repair pathways. Malignant cells acquire hallmark capabilities including sustained growth signalling, evasion of apoptosis, angiogenesis, tissue invasion, and metastasis to distant sites. Tumours are classified by tissue of origin (for example carcinomas from epithelium, sarcomas from connective tissue, and lymphomas and leukaemias from haematopoietic cells), by histological grade, and by anatomical stage, which together guide prognosis and therapy. Management combines surgery, radiotherapy, cytotoxic chemotherapy, targeted agents, and immunotherapy, increasingly directed by molecular and imaging biomarkers. Research published in this area spans head and neck malignancies including nasopharyngeal carcinoma and laryngeal squamous-cell carcinoma, the prognostic value of the neutrophil-to-lymphocyte ratio, thyroid and breast cancer epidemiology, and population-based cervical and colorectal cancer screening across diverse health systems. Work on the central nervous system's adaptive contribution to chronic disease and on therapeutic resistance during relapse reflects continuing interest in why some tumours evade cure. The journal publishes peer-reviewed clinical, epidemiological, and translational studies on cancer diagnosis, treatment, screening, and prevention.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 14 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Cancer, linking to each citing work.