Research Topic · Peer-Reviewed

Hyperglycemia

Hyperglycaemia is an abnormally elevated concentration of glucose in the blood, arising when insulin secretion, insulin action, or both are insufficient to maintain normal glucose homeostasis. It is the defining biochemical feature of diabetes mellitus but also occurs with physiological stress, certain medications, …

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 95× across the literature 🔖 ISSN 2574-450X

Overview

Hyperglycaemia is an abnormally elevated concentration of glucose in the blood, arising when insulin secretion, insulin action, or both are insufficient to maintain normal glucose homeostasis. It is the defining biochemical feature of diabetes mellitus but also occurs with physiological stress, certain medications, and endocrine disorders. Acutely, severe hyperglycaemia can precipitate diabetic ketoacidosis or a hyperosmolar hyperglycaemic state, while chronic elevation drives non-enzymatic glycation, oxidative stress, and endothelial dysfunction that underlie the microvascular and macrovascular complications of diabetes, including retinopathy, nephropathy, neuropathy, and cardiovascular disease. Management targets glucose lowering through diet, physical activity, oral hypoglycaemic agents, and insulin, guided by monitoring. Research in this area examines gene-therapy approaches to type 2 diabetes and the blood-glucose-lowering effects of plant-derived agents, including Trigonella foenum-graecum as an adjunct to glimepiride in streptozotocin-induced diabetic rats, Momordica charantia in type 2 diabetes, and Tridax procumbens inhibition of alpha-amylase. Further studies address pregnancy outcomes in gestational diabetes, self-management and quality of life in type 2 diabetes, the regulation of matrix metalloproteinase by glucose and insulin, and the effects of fennel and kale on metabolic parameters. The journal publishes peer-reviewed research on glucose metabolism, diabetes, and its complications.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 95 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Nov 2026.

A sample of recent works citing this journal's research on Hyperglycemia, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Journal of Obesity Management (ISSN 2574-450X).

Journal editorial board
Amit Surve · United States Bin Feng · China Joseph Fomusi Ndisang · Canada

This page summarises published research for orientation; it is not medical or professional advice.