Research Topic · Peer-Reviewed

Cholesterol

Cholesterol is a sterol lipid and an essential structural component of animal cell membranes, where it modulates fluidity, and a metabolic precursor of steroid hormones, bile acids, and vitamin D. Because it is insoluble in plasma, it is transported within lipoprotein particles; low-density lipoprotein (LDL) cholest…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 80× across the literature 🔖 ISSN 2574-450X 🗓 Reviewed June 2026

Overview

Cholesterol is a sterol lipid and an essential structural component of animal cell membranes, where it modulates fluidity, and a metabolic precursor of steroid hormones, bile acids, and vitamin D. Because it is insoluble in plasma, it is transported within lipoprotein particles; low-density lipoprotein (LDL) cholesterol delivers cholesterol to tissues and, when elevated, promotes atherosclerotic plaque, whereas high-density lipoprotein (HDL) mediates reverse cholesterol transport. Dyslipidaemia, an unfavourable balance of these fractions along with triglycerides, is a principal modifiable risk factor for coronary artery disease and stroke, addressed through diet, physical activity, and lipid-lowering agents such as statins. Research in this area examines hypolipidaemic and hypocholesterolaemic interventions, including the effects of fennel and its interaction with atorvastatin in obese rats, the effect of wheat germ and wheat germ oil on the lipid profile of hypercholesterolaemic rats, and a comparison of Momordica charantia with atorvastatin in fat-fed rats. Further studies address cholesterol-conjugated siRNA distribution in haematopoietic cells, the role of membrane cholesterol in liver calcium-ATPase activity, vitamin D receptor polymorphisms and dyslipidaemia in coronary artery disease, Framingham risk scoring, and culturally tailored lifestyle interventions that reduce cardiometabolic risk. The journal publishes peer-reviewed research on lipid metabolism and cardiometabolic health.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 80 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Cholesterol, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Obesity Management (ISSN 2574-450X).

Journal editorial board
Amit Surve · United States Paola Aceto · Italy Joseph Fomusi Ndisang · Canada

This page summarises published research for orientation; it is not medical or professional advice.