Research Topic · Peer-Reviewed

Polyacrylamide Gel Electrophoresis

Polyacrylamide gel electrophoresis is a laboratory technique that separates proteins or nucleic acids based on their size and charge by applying an electric field to samples embedded in a polyacrylamide gel matrix. Research published in this journal demonstrates the application of this technique across diverse areas…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 23× across the literature 🗓 Reviewed June 2026

Overview

Polyacrylamide gel electrophoresis is a laboratory technique that separates proteins or nucleic acids based on their size and charge by applying an electric field to samples embedded in a polyacrylamide gel matrix. Research published in this journal demonstrates the application of this technique across diverse areas of molecular biology and medicine. Studies have employed polyacrylamide gel electrophoresis to characterize protein dimerization and DNA-binding properties in plant transcription factors, where the method confirmed disulfide bond-mediated interactions. The technique has been utilized in proteomic investigations examining molecular biomarkers, cancer diagnostics, and personalized medicine applications, as well as in studies analyzing somatic mutations in signal transduction molecules associated with uterine leiomyosarcoma. Additional research has applied electrophoretic methods to assess protein stability in cell culture conditions, characterize myotoxic enzymes from snake venom, evaluate chemokine and kinase regulation, and investigate proteins involved in cellular senescence and tumor suppression. The technique has also supported nutritional studies examining skeletal muscle protein changes and genetic polymorphism research related to coronary heart disease risk. This breadth of applications underscores the fundamental role of polyacrylamide gel electrophoresis in protein and nucleic acid analysis across basic research, clinical diagnostics, and therapeutic development.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2018

Molecular Biomarkers: A Brief Review

Tarassishin LeonidCorresponding author
 Department of Biological Sciences.
Exact topic Proteomics and Genomics Research doi:10.14302/issn.2326-0793.jpgr-18-2418

How this research is being cited

The 12 articles above have been cited 23 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Polyacrylamide Gel Electrophoresis, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in New Developments in Molecular Biology.

Journal editorial board
Chengyue Zhang · United States MARINA PISCOPO · Italy

This page summarises published research for orientation; it is not medical or professional advice.