Research Topic · Peer-Reviewed

Thin-layer Chromatography

Thin-layer chromatography (TLC) is a laboratory technique used to separate and identify the components of a mixture. It works on the principle that different compounds travel at different rates across a thin layer of adsorbent material, the stationary phase, as a solvent, the mobile phase, moves through it by capill…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 90× across the literature 🔖 ISSN 2377-2549 🗓 Reviewed July 2026

Overview

Thin-layer chromatography (TLC) is a laboratory technique used to separate and identify the components of a mixture. It works on the principle that different compounds travel at different rates across a thin layer of adsorbent material, the stationary phase, as a solvent, the mobile phase, moves through it by capillary action. Components with a greater affinity for the stationary phase move more slowly, while those that interact more strongly with the solvent travel farther, producing a pattern of separated spots that can be compared, identified, or quantified. The stationary phase is typically a thin coating of silica gel or alumina on a glass, metal, or plastic backing. TLC is valued in chemistry for being rapid, inexpensive, and effective for analyzing complex mixtures. Research relevant to this technique includes phytochemical analysis and TLC profiling of plant extracts, the separation of benzoic esters in pharmaceutical products by glass chromatography, the identification and quantification of an adulterant in a dietary supplement, and the characterization of bioactive compounds from medicinal plants. These applications span natural-product chemistry, pharmaceutical analysis, and quality control. This page gathers peer-reviewed, open-access research relevant to thin-layer chromatography and related separation and analytical methods in chemistry.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 90 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Thin-layer Chromatography, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in New Developments in Chemistry (ISSN 2377-2549).

Journal editorial board
Annarita Del Gatto · Italy Bharat Gurale · United States Palani ELUMALAI · United Kingdom

This page summarises published research for orientation; it is not medical or professional advice.