Protein Interaction Networks

Protein interaction networks are an essential aspect of modern chemistry, involving a wide range of research techniques used to identify key protein-protein interactions that are integral to many physiological processes. By analyzing these networks, researchers can identify new drug targets and develop new therapies for a variety of diseases, including cancer, inflammation, diabetes, and neurodegenerative disorders. Recent advances in protein interaction network analysis have enabled researchers to identify key protein hubs that play a critical role in these networks. These hubs not only regulate communication and signaling between cells but are also involved in the changes associated with disease. One promising area of research involves the development of drugs that target these protein hubs, which can potentially be used to treat a wide range of diseases. The use of computational methods, such as machine learning and artificial intelligence, has been instrumental in the identification of new protein-protein interactions, as well as the prediction of the effects of specific protein interactions on biological systems. Ultimately, the study of protein interaction networks is critical in advancing our understanding of the molecular mechanisms underlying disease and developing new therapies to combat these conditions.

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42 article(s) found

Eukaryotic Signature Proteins

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Substrate Stiffness Influences the Time Dependence of CTGF Protein Expression in Müller Cells

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Human Myxomatous Mitral Valves Exhibit Focal Expression of Cartilage-Related Proteins

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Heart-Type Fatty Acid-Binding Protein Enables Rapid Risk Stratification in Patients with Pulmonary Embolism

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Correlation of Cryptococcal Antigen Assay with C-reactive Protein as Serum and Urine Biomarker in Cryptococcal Meningitis: Experience in a Tertiary Hospital

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Daily Saliva and Vaginal Mucins Co-vary in Protein-to-Carbohydrate Ratio

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Proteome and Proteomics: from Single Protein to Whole Body

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Correlation of Oncotype DX Recurrence Score with the Expression of Insulin Receptor Substrate Proteins in Estrogen Receptor + Breast Cancer

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Understanding Ubl-Rpn1 Intermolecular Interaction

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Overexpression of Prostate Apoptosis Response Protein-4 In Colon Cancer Cells Can Inhibit Metastasis by Upregulating E-cadherin Expression

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Investigations of Molecular Evolutionary Mechanisms in Partially Sequenced Heat Shock Protein70 Homologue-Coding Gene of Olive Leaf Yellowing-Associated Virus Isolates from Tunisia

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Influences of Australian nursing students’ anxiety, depression, personality and family interaction on their psychological well-being and suicidal ideation

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A Pilot Study Assessing the Impact of a High Protein Supplementation Diet on Fat Mass in Obese Adolescents with and without Type 2 Diabetes

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Bioinformatic Analysis of Coronary Disease Associated SNPs and Genes to Identify Proteins Potentially Involved in the Pathogenesis of Atherosclerosis

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Pharmaceutical intervention on Ca2+/cAMP signaling interaction: benefits for combating neurodegeneration and diseases related to aging

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Total Proteins, β- and γ-globulins as efficacy therapy response indicators in dogs infected with Leishmania infantum – a Review

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Blockade of Programmed Cell Death Protein-1 Pathway for the Treatment of Melanoma

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Identification and Expression Analysis of Fragaria Vesca MLO Genes Involved in Interaction with Powdery Mildew (Podosphaera Aphanis)

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Biological Networks: An Introductory Review

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Metal Metalloproteinase 2 is Differentially Regulated by the Interplay between Glucose and Insulin

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In Silico Inhibition of Essential Candida albicans Proteins by Arenicin, a Marine Antifungal Peptide

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Interaction Between Ator and Fennel in the Treatment of Obesity in Rats

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Adrenomedullin as a Protein with Multifunctional Behavior and Effects in Various Organs and Tissues

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Alpha-Fetoprotein and its Receptor: More Than Oncofoetal Antigens.

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Effect of a High Fat and High Protein Diet on Exercise-Induced Skeletal Muscle Hypertrophy in Rats

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Arbuscular Mycorrhizal Biofertilizers Sources in the Potato (Solanum Tuberosum) Plant show Interactions with Cultivars on Yield and Litter-bags Spectral Features

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RETRACTED: Monte Carlo Approach To Genotype By Environment Interaction Models

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Genetic Algorithm Coupled with Neural Networks to Guesstimate the Subsurface Features of the Earth

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Genetic-Mathematical Modelling of the Populations Interaction

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The Interaction Model of Concentrated Solar Radiation with Materials

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Survival Rate and Growth Performances on Pre-Grossing of the African Cyprinidae LabeobarbusBatesii (Boulenger, 1903) According to the Level of Dietary Protein

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Molecular Evolutionary Characteristics of the 2019 Novel Coronavirus (SARS-CoV-2) Contracted by Tunisian Citizens : Comparison and Relationship to Other Human and Animal Coronaviruses Based on Spike Glycoprotein-Coding Gene Sequences Analysis

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Modeling of the Deposition of Low-Density Lipoprotein Particles inside an Ideal Geometry of the Heart Coronary Arteries

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Marginal SARS-CoV-2 Spike Protein Increases Interferon and Balances Cytokine Gene Expression

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Functional properties of Watermelon (Citrullus lanatus) and Pumpkin seed flours and protein isolate

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Effect of Protein and Energy-Dense Nutritional Supplement with Immunonutrients on Cachexia in Cancer Patients: An Open-Label, Single-Arm Study Among Indian Patients

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Genotype x Environment Interaction and Yield Stability Analysis of Some Chickpea (Cicer arietinum L.) Genotypes across Different Environments in Sudan

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Novel Methods for Inhibiting Amyloidogenesis in the Presence of Peptides to Block Hydrophobic Interactions

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Rbm45 Phylogenetics, Protein Domain Conservation, and Gene Architecture in Clade Metazoa

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Understanding Inherited Bleeding Disorders: Genetic Mutations in Blood Coagulation Factors and Regulatory Proteins

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Retraction Note: Monte Carlo Approach To Genotype By Environment Interaction Models

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Interactions Between Natural Nuclear Reactors and Microbial Evolutionary Processes

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