Nitration is a chemical process in which a nitro group (NO₂) is introduced into an organic or inorganic compound, often occurring through reactions with nitric acid or nitrogen dioxide, and can also result from biological oxidative stress involving reactive nitrogen species. Research published in New Developments in…
Nitration is a chemical process in which a nitro group (NO₂) is introduced into an organic or inorganic compound, often occurring through reactions with nitric acid or nitrogen dioxide, and can also result from biological oxidative stress involving reactive nitrogen species. Research published in New Developments in Chemistry has examined nitration in the context of oxidative damage and biological systems. One study investigated how resveratrol prevents cataract formation by inhibiting pro-inflammatory mediators that can trigger oxidative stress in lens tissue, where protein nitration represents a form of post-translational modification associated with cellular damage. Another article explored the application of biofertilizers in agricultural systems, examining their effects on maize silage and meadows, which relates to nitrogen cycling and the potential formation of nitrogen-containing compounds in soil and plant systems. Understanding nitration matters because this process plays dual roles: it is essential in synthetic chemistry for producing pharmaceuticals, dyes, and explosives, while in biological contexts, excessive nitration of proteins and lipids serves as a marker of oxidative stress and inflammation linked to various pathological conditions. The interplay between controlled chemical nitration and undesired biological nitration remains an important area of investigation.
2 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 2 articles above have been cited 2 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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