Overview
Chromaffin cells are specialized neuroendocrine cells located primarily in the adrenal medulla that synthesize and secrete catecholamines, particularly epinephrine and norepinephrine, in response to stress and other physiological signals. Research published in Neurological Research and Therapy has examined chromaffin cell function and adrenal gland health from multiple perspectives. Studies have investigated how environmental toxicants such as aluminum sulphates affect adrenal gland structure and weight in experimental models, providing insight into potential mechanisms of endocrine disruption. Additional work has explored the role of nutritional interventions, specifically glycine supplementation, in restoring adrenal catecholamine secretion in models of hypothalamic obesity, demonstrating the connection between metabolic disorders and chromaffin cell function. The journal has also published research on calcium and cyclic AMP signaling pathways relevant to chromaffin cells, examining how pharmaceutical modulation of these signaling interactions may offer therapeutic benefits for neurodegenerative conditions and age-related diseases. This body of work underscores the importance of chromaffin cells not only in acute stress responses but also in broader contexts of metabolic health, environmental toxicology, and neurological disease, highlighting their significance as both research targets and potential therapeutic intervention points.
Research published in this journal
3 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Early Glycine Supplementation Re-Establishes Adrenal Catecholamine Secretion in Hypothalamic Obesity Model in Rats but does not Affect Visceral Adiposity.
Pharmaceutical intervention on Ca2+/cAMP signaling interaction: benefits for combating neurodegeneration and diseases related to aging
How this research is being cited
The 3 articles above have been cited 5 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2020 · Elsevier eBooks
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2020 · Elsevier eBooks
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A. Caricati‐Neto et al. · 2020 ·
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A. Caricati‐Neto et al. · 2020 · Diagnosis and Management in Parkinson's Disease
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2017 · International Journal of Human Anatomy
A sample of recent works citing this journal's research on Chromaffin Cells, linking to each citing work.