Overview
Acid-base and electrolyte disorders encompass a range of conditions in which the body's balance of acids, bases, and essential minerals such as sodium, potassium, calcium, and magnesium becomes disrupted, affecting cellular function and organ systems. These disorders frequently arise in the context of kidney disease, medication effects, and metabolic disturbances, requiring careful clinical assessment and management. Research published in Nephrology Advances has examined complications associated with newer therapeutic agents, including a documented case of acute bilateral hydronephrosis following dapagliflozin use, illustrating how sodium-glucose cotransporter-2 inhibitors can produce unexpected renal and electrolyte consequences. Such case reports contribute to the clinical understanding of drug-induced nephropathy and the spectrum of adverse effects that may accompany diabetes medications with renal mechanisms of action. The topic remains clinically significant because acid-base and electrolyte imbalances can rapidly progress to life-threatening conditions if unrecognized, and because evolving pharmacotherapies continue to introduce novel patterns of metabolic and renal dysfunction. Understanding these disorders supports nephrologists and other clinicians in preventing, diagnosing, and treating complications that span acute care settings and chronic disease management.
Research published in this journal
1 peer-reviewed article, ranked by relevance. Each links to its DOI.
How this research is being cited
The 1 article above has been cited 2 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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Shi-Xing Ma et al. · 2018 · Journal Of Nephrology Advances
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2018 · Journal Of Nephrology Advances
A sample of recent works citing this journal's research on Acid-Base and Electrolyte Disorders, linking to each citing work.