Overview
Cancer biology is the study of the molecular, cellular, and physiological processes through which normal cells become malignant and tumors arise, grow, and spread. It examines how genetic mutations and epigenetic changes disrupt the control of cell proliferation, survival, and differentiation, and how these alterations confer the characteristic capabilities of cancer, including sustained growth signaling, evasion of growth suppression and cell death, replicative immortality, angiogenesis, and the capacity to invade and metastasize. The discipline investigates the initiation and development of tumors, the behavior of solid human tumor cells, and the role of genes such as tumor suppressors, illustrated by models in which loss of p53 promotes tumor formation. Beyond the transformed cell, cancer biology considers the tumor microenvironment, interactions with the immune system, and systemic influences on disease, including emerging perspectives on how the nervous system and adaptive physiological changes may shape tumor progression. Experimental approaches range from cell and animal models to molecular and bioinformatic analyses, and studies of dietary and chemical influences on carcinogenesis contribute to understanding causation and prevention. By elucidating the fundamental mechanisms that drive malignancy, cancer biology underpins efforts to detect cancer earlier, identify therapeutic targets, develop more effective and selective treatments, and ultimately prevent and control the disease across its many forms.
Research published in this journal
8 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Tumor Development in p53 Knockout Mice: A Review of Mice Deficient for p53
A Cancer Theory: The Central Nervous System’s Adaptive Changes Make Chronic Diseases Incurable
The Effect of Aqueous Extract of Ocimum gratissium (Linn) on 1, 2 - Dimethyl Hydrazine induced Colon Cancer in Male Wistar Rats
Evolution of the Solid Human Tumor Cells Properties in Various Experimental Systems in Vitro
Correlation of Oncotype DX Recurrence Score with the Expression of Insulin Receptor Substrate Proteins in Estrogen Receptor + Breast Cancer
Emerging Paradigms in Regenerative Medicine: Stem cell Therapies
Lung Cancer and Isolated Adrenal Metastases: Different Disease?
How this research is being cited
The 8 articles above have been cited 15 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
-
Osahon Daniel Abu et al. · 2025 · Trends in Pharmacology and Toxicology
-
2025 · Trends in Biological Sciences
-
2025 ·
-
2025 ·
-
F. O. Omoregie et al. · 2024 · FUDMA Journal of Sciences
-
W. Aboulthana et al. · 2024 · Heliyon
-
2024 · Heliyon
-
2024 · FUDMA Journal of Sciences
A sample of recent works citing this journal's research on Cancer Biology, linking to each citing work.