Overview
Sequence Tagged Site (STS) analysis is a powerful tool used in genomics and genetics to look at particular areas of the genome. By amplifying a specific region of DNA, STS analysis can give an in-depth look at that region. It is used to examine polymorphisms, which are differences in a gene or region that can affect a person’s risk for diseases, as well as for mapping of chromosomal regions. STS analysis can also be used to study gene expression and how gene variants can lead to changes in phenotype. Additionally, it is used in studies of gene families, to look for linkages between diseases and to identify new gene functions and regulatory pathways. As such, Sequence Tagged Site Analysis is an invaluable tool for research in genetics and genomics.