Translation

Elongation Factor 2 Translation elongation factor 2 (eEF2) is a protein that is responsible for catalyzing the elongation process during protein synthesis in the ribosome. It binds charged tRNAs and, in the presence of GTP, helps to catalyze the addition of amino acids to the growing polypeptide chain in the process of protein synthesis. Its presence is essential for the progression of mRNA translocation. Its structure is highly conserved among different species and hence, it is important to study its activity in order to understand the fundamental mechanisms of protein synthesis and the regulation of gene expression. Furthermore, eEF2 can be used as a prognostic marker for cancer, and its deficiency has been observed in several diseases such as muscular dystrophy and myositis.