Current Issue

Research Article

Concomitant in Vivo Voltammetric and Electrophysiological Analysis Indicate that Nociceptin/Orphanin FQ Affects Dopamine and then Serotonin Activities in Brain Substancia Nigra.

Francesco Crespi

Volume 2, Issue 3  ·  Pages 1–9  ·  23 April 2019  ·  10.14302/issn.2578-8590.ipj-19-2772

Concurrent voltammetric and electrophysiological recording in the substantia nigra, used to follow how nociceptin/orphanin FQ affects dopamine and then serotonin activity. The work is an example of mechanism established at the level of the neural circuit rather than inferred from behavior.

Review

Principles and Constants of the Golden Proportion as a Criterion in Donosological Diagnostics of the Functional States of The Body and in the Assessment of the Probability of their Changes

M. Karabayev, N. M. Gasanova, M. T. Botirov, G.S. Kosimova

Volume 2, Issue 3  ·  Pages 10–21  ·  25 January 2022

Opinion

The Heart Physiology in Fertile Female and The Heart Pathophysiology in Post Menopausal Female. The Contribution of Molecular Biology, Maintaining Cardiac Hemodinamy and Electrophysiology

Samuel Sclarosky

Volume 2, Issue 3  ·  Pages 22–26  ·  8 June 2024  ·  10.14302/issn.2578-8590.ipj-24-5107

Research Article

Reduced Tissue Oxygenation and Altered Valsalva Hemodynamics in Young Adults with Type 1 Diabetes

Maria Bitsch Poulsen, Peter Oketa-Onyut Julu, Memon Schah, Mussadiq Shah, Christina Brock

Volume 2, Issue 3  ·  Pages 27–43  ·  27 May 2026  ·  10.14302/issn.2578-8590.ipj-26-6121

A cross-sectional comparison of fifteen young adults with type 1 diabetes and fifteen age-matched controls, assessed with standardized cardiovascular autonomic reflex tests alongside continuous beat-to-beat blood pressure and transcutaneous tissue gas recording. Reflex ratios were preserved in both groups, while baseline tissue oxygenation was lower in the diabetes group and the blood-pressure response to the Valsalva maneuver differed across its phases. The authors read the two observations together as possible early signs of dysautonomia and state that longitudinal validation is required.