ANCA Vasculitis

Overview

ANCA vasculitis is a group of autoimmune disorders in which the immune system produces anti-neutrophil cytoplasmic antibodies (ANCA) that target proteins in certain white blood cells, leading to inflammation and damage of small blood vessels. This inflammation can narrow, weaken, or destroy the affected vessels, reducing blood flow and injuring the organs they supply. The condition most commonly affects the kidneys and respiratory tract but can involve many other systems, and its specific forms include granulomatosis with polyangiitis, microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis. Symptoms vary according to which organs are involved and may include fatigue, fever, joint and muscle pain, kidney impairment, respiratory problems, skin changes, and nerve involvement. Because ANCA vasculitis can progress rapidly and threaten organ function, prompt diagnosis, often supported by antibody testing, imaging, and biopsy, is important, and treatment typically relies on immunosuppressive therapy to control the immune response and prevent relapse. Within the scope of the International Journal of Vasculitis, which addresses inflammatory diseases of the blood vessels, this page gathers peer-reviewed, open-access research relevant to vasculitis and related autoimmune and renal conditions.

Research published in this journal

2 peer-reviewed articles, ranked by relevance. Each links to its DOI.

This page summarises published research for orientation; it is not medical or professional advice.

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