Steroids are a class of lipid-soluble organic compounds defined by a characteristic fused four-ring gonane skeleton of three six-membered rings and one five-membered ring. They include the steroid hormones, such as glucocorticoids, mineralocorticoids, androgens, estrogens, and progestogens, as well as sterols like c…
Steroids are a class of lipid-soluble organic compounds defined by a characteristic fused four-ring gonane skeleton of three six-membered rings and one five-membered ring. They include the steroid hormones, such as glucocorticoids, mineralocorticoids, androgens, estrogens, and progestogens, as well as sterols like cholesterol, from which the hormones are biosynthesized, and bile acids and vitamin D derivatives. As signalling molecules, steroid hormones diffuse across cell membranes and act largely through intracellular nuclear receptors that regulate gene transcription, controlling metabolism, growth, development, electrolyte balance, reproduction, and immune and inflammatory responses. Their anti-inflammatory and immunosuppressive properties make synthetic corticosteroids important therapeutics in conditions such as asthma, arthritis, autoimmune disease, and acute inflammation, while anabolic steroids and their misuse raise distinct pharmacological and clinical concerns. Research relevant to this area includes the use of corticosteroids combined with anti-VEGF agents in retinal vein occlusion and dexamethasone pulse therapy in refractory childhood seizure disorders, illustrating therapeutic applications of glucocorticoids. The journal publishes peer-reviewed research on steroids and steroid hormones, their biochemistry and receptor-mediated actions, and the clinical use of corticosteroid and related steroidal agents.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 88 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Steroids, linking to each citing work.